Development and Validation of a Kidney-Transplant Specific Measure of Treatment Burden.
Development and Validation of a Kidney-Transplant Specific Measure of Treatment Burden.
复制标题
DOI：
10.1186/s12882-022-02923-3
复制
发表时间：
2022-09-03
期刊：
影响因子：
2.3
通讯作者：
Eton, David T.
中科院分区：
文献类型：
--
作者：
Lorenz, Elizabeth C.;Petterson, Tanya M.;Zaniletti, Isabella;Lackore, Kandace A.;Johnson, Bradley K.;Mai, Martin L.;Nair, Sumi S.;Bentall, Andrew J.;Yost, Kathleen J.;Eton, David T.
治疗负担是指管理个人健康及其对福祉的影响所涉及的工作，并与慢性病患者的不依从性有关。没有肾移植（KT）治疗负担的具体措施存在。本研究的目的是开发一个KT特定的补充与治疗和自我管理（PETS），治疗负担的一般措施的患者经验。在起草和预测试KT特定的调查项目后，我们进行了一项横断面调查研究，涉及明尼苏达州、亚利桑那州和佛罗里达州马约诊所的KT接受者。探索性因素分析（EFA）被用来确定域缩放KT特定的补充。结构和已知组的有效性进行了测定。调查受访者（n = 167）的平均年龄为61岁（范围22-86），平均接受KT 4.0年前。确定了三个KT特异性量表（移植功能、自我管理、不良反应）。KT特异性量表得分越高，PETS治疗负担越重，身心健康状况越差，自我效能感越低（p < 0.0001）。服用更多药物的患者报告了更高的移植自我管理负担。我们开发了一个KT特定的补充PETS治疗负担的一般措施。分数可以帮助提供者识别处于不依从风险中的接收者。在线版本包含补充材料，可通过10.1186/s12882-022-02923-3获得。
Treatment burden refers to the work involved in managing one’s health and its impact on well-being and has been associated with nonadherence in patients with chronic illnesses. No kidney transplant (KT)-specific measure of treatment burden exists. The aim of this study was to develop a KT-specific supplement to the Patient Experience with Treatment and Self-Management (PETS), a general measure of treatment burden. After drafting and pretesting KT-specific survey items, we conducted a cross-sectional survey study involving KT recipients from Mayo Clinic in Minnesota, Arizona, and Florida. Exploratory factor analysis (EFA) was used to identify domains for scaling the KT-specific supplement. Construct and known-groups validity were determined. Survey respondents (n = 167) had a mean age of 61 years (range 22–86) and received a KT on average 4.0 years ago. Three KT-specific scales were identified (transplant function, self-management, adverse effects). Higher scores on the KT-specific scales were correlated with higher PETS treatment burden, worse physical and mental health, and lower self-efficacy (p < 0.0001). Patients taking more medications reported higher transplant self-management burden. We developed a KT-specific supplement to the PETS general measure of treatment burden. Scores may help providers identify recipients at risk for nonadherence. The online version contains supplementary material available at 10.1186/s12882-022-02923-3.
登录
查看更多内容
影响因子：
2.1
作者：
Lorenz, Elizabeth C.;Cheville, Andrea L.;LeBrasseur, Nathan K.
通讯作者：
LeBrasseur, Nathan K.
影响因子：
8.8
作者：
Hart, A.;Lentine, K. L.;Snyder, J. J.
通讯作者：
Snyder, J. J.
影响因子：
6.2
作者：
Howell, Martin;Wong, Germaine;Howard, Kirsten
通讯作者：
Howard, Kirsten
影响因子：
3.6
作者：
Atkinson, Mark J;Sinha, Anusha;Rowland, Clayton R
通讯作者：
Rowland, Clayton R
影响因子：
3.8
作者：
通讯作者：
--