Habituation of prepulse inhibition of the startle reflex using an auditory prepulse close to background noise.
Habituation of prepulse inhibition of the startle reflex using an auditory prepulse close to background noise.
复制标题
使用接近背景噪声的听觉前脉冲来习惯惊吓反射的前脉冲抑制。
DOI：
10.1037//0735-7044.109.3.388
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发表时间：
1995
影响因子：
1.9
通讯作者：
Davis,M
中科院分区：
文献类型：
--
作者：
Gewirtz,JC;Davis,M
这项研究考察了脉冲前抑制是否习惯于单独重复呈现脉冲前脉冲。预脉冲抑制是通过测量当听觉预脉冲先于声学惊吓刺激时，惊吓反应的减少量来确定的。大鼠接受相同听觉预脉冲的重复暴露(实验条件)和视觉预脉冲的重复暴露(对照条件)。为了减少惊吓本身的习惯化，以及惊吓刺激可能对脉冲前抑制习惯化可能产生的去习惯化影响，惊恐刺激呈现很少被穿插在大量的脉冲前单独呈现中。使用高于背景噪声的2.5分贝的听觉预脉冲，而不是13分贝的听觉预脉冲，刺激特异性的脉冲抑制习惯化发生。讨论了脉冲前抑制在感觉门控中的作用。(保留所有权利。)
This study examined whether prepulse inhibition habituates with repeated presentation of the prepulse alone. Prepulse inhibition was determined by measuring the decrement in the startle response when the acoustic startle-eliciting stimulus was preceded by an auditory prepulse. Rats received repetitive exposures of the same auditory prepulse alone (experimental condition) and of a visual prepulse alone (control condition). To reduce habituation of startle itself and the possible dishabituating influence the startle stimulus might have on habituation of prepulse inhibition, startle stimulus presentations were infrequently interspersed among a much larger number of prepulse-alone presentations. Stimulus-specific habituation of prepulse inhibition occurred using an auditory prepulse 2.5 dB, but not 13 dB, above background noise. Implications are discussed for the role of prepulse inhibition in sensory gating.(PsycInfo Database Record (c) 2022 APA, all rights reserved)