CIRCADIAN PERIODICITY OF PHYSIOLOGICAL FUNCTIONS IN DIFFERENT STAGES OF INFANCY AND CHILDHOOD
CIRCADIAN PERIODICITY OF PHYSIOLOGICAL FUNCTIONS IN DIFFERENT STAGES OF INFANCY AND CHILDHOOD
复制标题
婴儿期和儿童期不同阶段生理功能的昼夜周期性
DOI：
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发表时间：
1964
影响因子：
5.2
通讯作者：
K. Stehr
中科院分区：
文献类型：
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作者：
T. Hellbrügge;J. Lange;J. Rutenfranz;K. Stehr
在第25届冷泉港研讨会上…定量生物学我们之一（Hellbrugge’）报道了生命第一年某些身体功能的昼夜节律变化，考虑到心脏频率、体温、睡眠-觉醒模式、皮肤电阻抗和各种肾脏功能等单一功能的变化，我们对婴儿昼夜周期变化的发展得到以下结果：不同的生理功能各自独立地形成一定的昼夜节律。2. 不同功能的昼夜节律在出生后的不同时间变得明显。3. 在昼夜节律周期的发展过程中，振荡范围的增加发生在所有生理功能中。4. 在某些情况下，这种范围的增加更多地是由于在光明时段振荡的上宽度的增加，而在另一些情况下则是由于在黑暗时段振荡的下宽度的增加。2 5。在人类，同样，单相昼夜节律似乎起源于多相周期。6. 对于昼夜节律的发展，婴儿出生时的成熟是至关重要的。早产儿的昼夜节律周期比足月出生的婴儿发育得晚。这个关于昼夜节律周期发展的论述的意义和目的不是分析每个周期功能本身，而是把每个功能首先发展的儿童的不同年龄放在关注的中心。我们在儿童发育的特殊时期所研究的功能需要与他们的昼夜周期阶段进行比较。
Pediatric Policlinic of the University of Munich, Munich, Germany At the 25th Cold Spring Harbor Symposium on ..Quantitative Biology one of us (Hellbrugge') reported on circadian rhythmic changes of certain body functisns during the first year of life, Considering the changes of single functions as the heart frequency, body temperature, sleep-wakefulness pattern, electrical skin resistance and various renal functions we obtained the following results on the development of diurnal periodical changes in infants : 1. Different physiologic functions develop a certain circadian rhythm independently from each other. 2. The circadian rhythm of the different functions becomes apparent a t different times after birth. 3. During the development of circadian periodicity an increase in the range of oscillation occurs in all physiologic functions. 4. This increase of range in some cases is caused more by the increase of the upper width of oscillation during the light hours, in others by the increase of the lower width of oscillation during the dark hours.2 5. In man, also, the monophasic circadian rhythm seems to originate out of polyphasic cycles. 6. For the development of circadian rhythm the maturity of the child at birth is of essential importance. The circadian periodicity develops later in premature than in children born at term. The meaning and purpose of this exposition on the development of a circadian periodicity will not be to analyze each periodical function for itself, but to place in the center of attention the different ages of childhood a t which each function will develop first. The functions we investigated in special periods of child development a re to be compared with regard to the stage of their circadian periodicity.