X-RAY DUAL-PHOTON ABSORPTIOMETRY - A NEW METHOD FOR THE MEASUREMENT OF BONE-DENSITY
X-RAY DUAL-PHOTON ABSORPTIOMETRY - A NEW METHOD FOR THE MEASUREMENT OF BONE-DENSITY
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DOI：
10.1259/0007-1285-62-739-587
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发表时间：
1989-07-01
影响因子：
2.6
通讯作者：
RYDER, JP
中科院分区：
文献类型：
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作者：
CULLUM, ID;ELL, PJ;RYDER, JP
最近引入的一种能够测量人体骨骼密度（目前在脊柱和臀部，但最终用于全身）的方法（双光子X射线吸收测定法，DEXA）已被评估其长期评估骨密度变化的能力。该方法使用X射线而不是γ射线。射线作为其光子源，在图像质量和结果的精度（可再现性）方面都表现出优于现有系统的显著改进，其在体内优于1%。与现有技术相比，扫描时间大约减半，辐射剂量减少了25%。给出了有关结果长期漂移和患者成分（即厚度和脂肪含量）变化影响的第一批数据，并表明新方法上级目前的放射性核素系统。这种新方法很可能成为骨密度测量的标准。
A recently introduced method (dual-photon X-ray absorptiometry, DEXA) capable of measuring skeletal density in man (at present in the spine and hips, but ultimately for the whole body) has been evaluated in terms of its ability to perform long-term assessment of bone density changes. The method, which uses X rays rather than .gamma. rays as its photon source, represents a significant improvement over present systems both in image quality and precision (reproducibility) of results, which is better than 1% in vivo. Scanning time is approximately halved compared with present techniques and the radiation dose is reduced by 25%. First data on long-term drift of results and effects of changes in patient composition (i.e. thickness and fat content) are given and show the new method to be superior to present radionuclide systems. It is likely that this new method will become the standard for bone density measurements.