Entry into a new class of potent proteasome inhibitors having high antiproliferative activity by structure-based design
Entry into a new class of potent proteasome inhibitors having high antiproliferative activity by structure-based design
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DOI：
10.1021/jm049660v
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发表时间：
2004-09-23
影响因子：
7.3
通讯作者：
García- Echeverría, C
中科院分区：
文献类型：
--
作者：
Furet, P;Imbach, P;García- Echeverría, C
Proteasome inhibition is a therapeutic concept of current interest in anticancer research. We report here the design, synthesis, and biological characterization of prototypes of a new class of noncovalent proteasome inhibitors showing high activity in biochemical and cellular assays.
