Spiral Analysis: A New Technique for Measuring Tremor With a Digitizing Tablet
Spiral Analysis: A New Technique for Measuring Tremor With a Digitizing Tablet
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螺旋分析：使用数字化平板测量震颤的新技术
DOI：
10.1002/mds.870131315
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发表时间：
2008
影响因子：
8.6
通讯作者：
S. Pullman
中科院分区：
文献类型：
--
作者：
S. Pullman
描述了一种新的量化震颤和其他运动功能障碍的计算方法。通过使用连接到微型计算机的数字化平板，这种分析是从手写的阿基米德螺线得出的。这项技术将螺旋绘制的标准临床神经学测试扩展为一种客观和准确的测量，可以自动检测、表征和量化运动障碍患者的运动功能障碍。此外，它安全、廉价、快速、便携、非侵入性，可以在不需要电线或其他附件的情况下对大量患者进行治疗。螺旋数据在X、Y和压力轴上收集，提供虚拟的“三轴”记录。螺旋分析被证明能够在早期阶段评估可能预示临床问题的细微运动异常，从而允许最合理的基因测试、治疗或预防形式。螺旋分析可以作为临床参与的初始标志，或作为治疗干预后变化的客观衡量标准。
A new computational method for quantification of tremor and other aspects of motor dysfunction is described. By using a digitizing tablet connected to a microcomputer, this analysis is derived from the handwritten Archimedean spiral. This technique extends the standard clinical neurologic test of spiral drawing into an objective and accurate measure that can automatically detect, characterize, and quantify motor dysfunction in patients with movement disorders. Further, it is safe, inexpensive, fast, portable, noninvasive, and can be administered to a large cohort of patients without the need for wires or other attachments. Spiral data are collected in the X, Y, and pressure axes, providing virtual “triaxial” recordings. Spiral analysis is shown to be capable of assessing subtle motor abnormalities potentially indicative of clinical problems in their earliest stages, and thus allow the most rational forms of genetic testing, treatment, or prevention. Spiral analysis may be useful as an initial marker of clinical involvement or serve as an objective gauge of change after therapeutic intervention.