Nuclear to Cytoplasmic Translocation of Heterogeneous Nuclear Ribonucleoprotein U Enhances TLR-Induced Proinflammatory Cytokine Production by Stabilizing mRNAs in Macrophages

Nuclear to Cytoplasmic Translocation of Heterogeneous Nuclear Ribonucleoprotein U Enhances TLR-Induced Proinflammatory Cytokine Production by Stabilizing mRNAs in Macrophages
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异质核核糖核蛋白 U 的核到细胞质易位通过稳定巨噬细胞中的 mRNA 增强 TLR 诱导的促炎细胞因子的产生

DOI:
10.4049/jimmunol.1101175
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发表时间:
2012-04
期刊:
The Journal of Immunology
影响因子:
--
通讯作者:
Gao, Chengjiang
Gao, Chengjiang
中科院分区:
其他
文献类型:
--
作者:
Zhao, Wei;Wang, Lijuan;Zhang, Meng;Wang, Peng;Qi, Jianni;Zhang, Lei;Gao, Chengjiang

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TLR signaling is associated with the transcription of various proinflammatory cytokines, including TNF-α, IL-6, and IL-1β. After transcription, the mRNA of these proinflammatory cytokines needs to be tightly controlled at the posttranscriptional level to
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