Regulation of polar auxin transport by protein and lipid kinases.
Regulation of polar auxin transport by protein and lipid kinases.
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DOI：
10.1093/jxb/erw216
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发表时间：
2016-07
影响因子：
6.9
通讯作者：
Jaillais Y
中科院分区：
文献类型：
--
作者：
Armengot L;Marquès-Bueno MM;Jaillais Y
生长素的定向运输，称为极性生长素运输，允许这种激素在不同细胞和组织中不对称分布。该系统产生局部生长素最大值、最小值和梯度，这有助于器官的形成和形状的确定。因此，极性生长素运输对于植物发育的各个方面都至关重要，而且对于环境相互作用也至关重要，特别是在根据环境塑造植物结构方面。细胞间的生长素运输是由生长素载体网络介导的，该网络在转录和翻译后水平上受到调节。在这里，我们回顾了目前对生长素运输“非基因组”调节某些方面的知识，重点关注蛋白质和脂质激酶的磷酸化如何控制生长素载体的极性、细胞内运输、稳定性和活性。我们描述了几种 AGC 激酶（包括 PINOID、D6PK 和蓝光光感受器 phot1）在磷酸化 PIN 和 ABCB 家族生长素载体中的作用。我们还强调了一些受体样激酶 (RLK) 和双组分组氨酸激酶受体在极性生长素转运中的功能，注意到可能有 RLK 参与协调生长素分布尚未被发现。此外，我们描述了磷脂磷酸化在极性建立和 PIN 蛋白细胞内运输中的新作用。我们在初生根和侧根发育、叶细胞形状获得以及根向地性和芽向光性的背景下概述了这些不同的磷酸化机制。
The directional transport of auxin, known as polar auxin transport, allows asymmetric distribution of this hormone in different cells and tissues. This system creates local auxin maxima, minima and gradients that are instrumental in both organ initiation and shape determination. As such, polar auxin transport is crucial for all aspects of plant development but also for environmental interaction, notably in shaping plant architecture to its environment. Cell-to-cell auxin transport is mediated by a network of auxin carriers that are regulated at the transcriptional and post-translational levels. Here we review our current knowledge on some aspects of the ‘non-genomic’ regulation of auxin transport, putting an emphasis on how phosphorylation by protein and lipid kinases controls the polarity, intracellular trafficking, stability and activity of auxin carriers. We describe the role of several AGC kinases, including PINOID, D6PK and the blue light photoreceptor phot1, in phosphorylating auxin carriers from the PIN and ABCB families. We also highlight the function of some Receptor-Like Kinases (RLK) and two-component histidine kinase receptors in polar auxin transport, noticing that there are likely RLKs involved in coordinating auxin distribution yet to be discovered. In addition, we describe the emerging role of phospholipid phosphorylation in polarity establishment and intracellular trafficking of PIN proteins. We outline these various phosphorylation mechanisms in the context of primary and lateral root development, leaf cell shape acquisition as well as root gravitropism and shoot phototropism.