An assessment of factors contributing to treatment adherence and knowledge of TB transmission among patients on TB treatment.
An assessment of factors contributing to treatment adherence and knowledge of TB transmission among patients on TB treatment.
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DOI：
10.1186/1471-2458-4-68
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发表时间：
2004-12-29
影响因子：
4.5
通讯作者：
Sikaona L
中科院分区：
文献类型：
--
作者：
Kaona FA;Tuba M;Siziya S;Sikaona L
根据短期直接观察治疗（DOTS）制定的结核病治疗指南是赞比亚结核病治疗的一项共同战略。该研究在赞比亚恩多拉进行，旨在调查导致结核病治疗患者不依从治疗的因素和对结核病传播的了解，以便设计一种基于社区的干预措施，以促进依从性。在恩多拉的六个随机选择的集水区进行了一项以家庭为基础的调查，在六个月内接受结核病治疗的736名病人中，有400人是通过区卫生管理委员会诊所招募的。所有患者均采用预先测试的结构化问卷进行访谈，包括i。社会人口特征。三、社会经济因素。结核病的传播和预防知识。家庭一级寻求健康的行为模式和结核病治疗做法。大多数男性结核病患者答复者往往比女性结核病患者答复者年龄更大，受教育程度更高。总体而言，29.8%的患者停止服用药物。有39.1%的女性和33.9%的男性报告说，结核病患者在开始治疗的前2个月内停止服用药物。年龄、婚姻状况和教育水平与依从性无显著相关。导致不依从的主要因素包括患者感觉开始好转（45.1%和38.6%）、对完成疗程的益处缺乏了解（25.7%）、家中药物用完（25.4%）和结核病药物太强（20.1%和20.2%）。在调整年龄、婚姻状况和教育水平后，结核病知识有显著差异[OR = 1.66，95%CI 1.23，2.26]，男性多于女性报告共用杯子是结核病传播的手段。显著[p = 0.016]更多在研究中居住不到两年的患者（59%）更有可能报告结核病的母婴传播，而在该地区居住超过2年的患者为41.2%。这项研究确定，29.8%的结核病患者在开始感觉好转后未能遵守结核病药物服用方案。
The treatment guidelines for tuberculosis treatment under Directly Observed Treatment, Short-course (DOTS) have been a common strategy for TB treatment in Zambia. The study was carried out in Ndola, Zambia, to investigate factors contributing to treatment non-adherence and knowledge of TB transmission among patients on TB treatment, in order to design a community-based intervention, that would promote compliance. A household-based survey was conducted in six randomly selected catchment areas of Ndola, where 400 out of 736 patients receiving TB treatment within the six months period, were recruited through the District's Health Management Board (DHMB) clinics. All patients were interviewed using a pre-tested structured questionnaire, consisting of i. Socio-demographic characteristics ii. Socio-economic factors iii. Knowledge about TB transmission and prevention iv. Patterns in health seeking behaviour and v. TB treatment practices at household level. Most male TB patient respondents tended to be older and more educated than the female TB patient respondents. Overall, 29.8% of the patients stopped taking their medication. There were 39.1% of the females and 33.9% of the males, who reported that TB patients stopped taking their medication within the first 2 months of commencing treatment. Age, marital status and educational levels were not significantly associated with compliance. The major factors leading to non-compliance included patients beginning to feel better (45.1% and 38.6%), lack of knowledge on the benefits of completing a course (25.7%), running out of drugs at home (25.4%) and TB drugs too strong (20.1% and 20.2%). There was a significant difference [OR = 1.66, 95% CI 1.23, 2.26] in TB knowledge, with more males than females reporting sharing of cups as a means for TB transmission, after adjusting for age, marital status and educational levels. Significantly [p = 0.016] more patients who had resided in the study for less than two years (59%) were more likely to report mother to child transmission of TB, compared to 41.2% of those who had been in the area for more than 2 years. This study established that 29.8% of TB patients failed to comply with TB drug taking regimen once they started feeling better.
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影响因子：
4.5
作者：
Odusanya OO;Babafemi JO
通讯作者：
Babafemi JO
影响因子：
3.3
作者：
Auer, C;Sarol, J;Weiss, M
通讯作者：
Weiss, M
DOI：
10.1177/146642409211200202
发表时间：
1992-04-01
期刊：
JOURNAL OF THE ROYAL SOCIETY OF HEALTH
影响因子：
--
作者：
ODEBIYI, AI
通讯作者：
ODEBIYI, AI
影响因子：
5.4
作者：
Steen, TW;Mazonde, GN
通讯作者：
Mazonde, GN
影响因子：
3.8
作者：
SOMERVILLE, MA;ORKIN, AJ
通讯作者：
ORKIN, AJ