3D structures of fungal partitiviruses.

3D structures of fungal partitiviruses.
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DOI:
10.1016/b978-0-12-394315-6.00003-9
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发表时间:
2013
影响因子:
--
通讯作者:
Tao YJ
Tao YJ
中科院分区:
医学2区
文献类型:
--
作者:
Nibert ML;Tang J;Xie J;Collier AM;Ghabrial SA;Baker TS;Tao YJ

文献摘要

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Partitiviruses是目前公认的九个具有双链RNA基因组的病毒家族之一。分型病毒基因组是双片段的,并且每个基因组片段包装在单独的病毒衣壳内。不同的分离病毒感染植物、真菌或原生动物。最近的研究终于阐明了三种代表性真菌partitivirus的病毒粒子的三维结构。这些结构包括许多独特的特征,允许与来自其他家族的dsRNA病毒的结构进行信息比较。结果和比较表明,这些病毒的功能,组装和进化的几个新的结论。
Partitiviruses constitute one of the nine currently recognized families of viruses with encapsidated, double-stranded (ds)RNA genomes. The partitivirus genome is bisegmented, and each genome segment is packaged inside a separate viral capsid. Different partitiviruses infect plants, fungi, or protozoa. Recent studies have at last shed light on the three-dimensional (3-D) structures of the virions of three, representative fungal partitiviruses. These structures include a number of distinctive features, allowing informative comparisons with the structures of dsRNA viruses from other families. The results and comparisons suggest several new conclusions about the functions, assembly, and evolution of these viruses.