Visual field and optic disc progression in patients with different types of optic disc damage - A longitudinal prospective study
Visual field and optic disc progression in patients with different types of optic disc damage - A longitudinal prospective study
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DOI：
10.1016/s0161-6420(03)00801-7
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发表时间：
2003-11-01
期刊：
影响因子：
13.7
通讯作者：
Chauhan, BC
中科院分区：
文献类型：
--
作者：
Nicolela, MT;McCormick, TA;Chauhan, BC
目的：评估具有不同视盘损伤模式的青光眼患者视野和视盘进展的发生率。设计：前瞻性、观察性病例系列。参与者：105 名开角型青光眼患者。方法：由 2 名蒙面观察者审查 105 名患者的 105 只研究眼睛的基线视盘照片，并根据视盘损伤模式分为以下几类：局灶性、近视性、老年性硬化性和普遍的椎间盘损伤。每 6 个月对患者进行一次标准自动视野检查 (SAP)、高通分辨率视野检查 (HRP) 和海德堡视网膜断层扫描仪扫描激光断层扫描 (SLT) 随访。主要结果指标：根据预先定义的标准确定视野（SAP 和 HRP）和视盘（SLT）进展。结果：24 只眼睛被分为局灶性、8 只近视、12 只老年硬化型，28分为广义组。观察者无法将 33 名患者的眼睛分为任何一组，因此被排除在进一步分析之外。尽管四组随访期间的眼压相似，但观察到进展频率存在一些差异。老年硬化症椎间盘患者的视野进展（SAP 和 HRP）和视盘进展率最低，但差异仅在视盘进展方面显着（P = 0.05）。 结论：与其他类型椎间盘损伤的患者相比，老年硬化症椎间盘患者表现出视野和视盘进展较少的趋势。 (C) 2003 年由美国眼科学会颁发。
Objective: To evaluate the incidence of visual field and optic disc progression in glaucoma patients with distinct patterns of optic disc damage.Design: Prospective, observational case series.Participants: One hundred five patients with open-angle glaucoma.Methods: Baseline optic disc photographs of 105 study eyes of 105 patients were reviewed by 2 masked observers and classified according to patterns of disc damage into the following categories: focal, myopic, senile sclerotic, and generalized disc damage. Patients were followed up every 6 months with standard automated perimetry (SAP), high-pass resolution perimetry (HRP), and scanning laser tomography (SLT) with the Heidelberg Retina Tomograph.Main Outcome Measures: Visual field (SAP and HRP) and optic disc (SLT) progression were determined according to predefined criteria.Results: Twenty-four eyes were classified into the focal, 8 into the myopic, 12 into the senile sclerotic, and 28 into the generalized group. Eyes from 33 patients could not be classified by the observers into any of these groups and were excluded from further analysis. Although intraocular pressure during follow-up was similar among the four groups, some differences in frequency of progression were observed. Patients with senile sclerotic discs had the lowest rates of visual field progression (both with SAP and HRP) and optic disc progression, although the differences were significant only for optic disc progression (P = 0.05).Conclusions: Patients with senile sclerotic discs showed a tendency towards less visual field and optic disc progression when compared with patients with other types of disc damage. (C) 2003 by the American Academy of Ophthalmology.