FUNCTIONAL SIGNIFICANCE OF CELL SIZE IN SPINAL MOTONEURONS
FUNCTIONAL SIGNIFICANCE OF CELL SIZE IN SPINAL MOTONEURONS
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DOI：
10.1152/jn.1965.28.3.560
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发表时间：
1965-01-01
影响因子：
2.5
通讯作者：
CARPENTER, DO
中科院分区：
文献类型：
--
作者：
HENNEMAN, E;SOMJEN, G;CARPENTER, DO
在去大脑猫的招聘的顺序，个别运动神经元放电反射响应拉伸的三头肌进行了比较，从他们的轴突记录在腹根细丝的脉冲的幅度。在165对单位中的142 1/2中，较小的神经元，即，轴突产生较小冲动的细胞具有较低的拉伸阈值，而较大细胞具有较高的阈值。当拉伸被释放时，单位以与其招募相反的顺序“退出”放电（236对中的225对）。一般来说，对紧张性反应的单位比对阶段性反应的单位小。本文对尺寸与兴奋性的关系作了初步的解释。根据池中细胞的大小和兴奋性，对“分离”、“放电区”、“阈下边缘”、“易化”和“闭塞”进行了简要的重新定义。有人指出，细胞大小决定了整体的放电频率或“使用”的运动神经元，并讨论了一些影响。
In decerebrate cats the order of recruitment of individual motor neurons discharging reflexly in response to stretch of the triceps muscle was compared with the amplitude of the impulses recorded from their axons in ventral root filaments. In 142 1/2 out of 165 pairs of units the smaller neuron, i.e., the one whose axon yielded the smaller impulses, had the lower threshold to stretch and the larger cell had the higher threshold. When stretch was released units "dropped out" of the discharge in the reverse order of their recruitment (225 out of 236 pairs). Units which responded tonically were, in general, smaller than those which responded phasically. A tentative explanation of the relation between size and excitability is advanced. "Fractionation", "discharge zone," "subliminal fringe," "facilitation" and "occlusion" are redefined briefly in terms of the sizes and excitability of the cells in a pool. It is pointed out that cell size determines the overall frequency of discharge or "usage" of a motor neuron, and some implications of this are discussed.