A TEN ‐ YEAR FOLLOW ‐ UP OF CHILDREN OF SCHIZOPHRENIC MOTHERS CLINICAL ASSESSMENT
A TEN ‐ YEAR FOLLOW ‐ UP OF CHILDREN OF SCHIZOPHRENIC MOTHERS CLINICAL ASSESSMENT
复制标题
精神分裂症母亲的孩子十年临床评估随访
DOI：
--
复制
发表时间：
1976
影响因子：
6.7
通讯作者：
H. Schulsinger
中科院分区：
文献类型：
--
作者：
H. Schulsinger
自1962年以来，一项基于梅德尼克精神分裂症学习理论的前瞻性研究对207名母亲患有严重精神分裂症的受试者和104名父母或祖父母中没有已知精神疾病的匹配受试者进行了跟踪调查。本文描述了基于1972-1974年的随访检查的临床结果的分析。这项检查包括使用三种方法(两种使用计算机得出的诊断和一种传统的临床访谈)进行的3.5小时的临床访谈。173名高危受试者和91名低危受试者进行了全面的临床重新评估。在评估时，他们的年龄在18岁到30岁之间。诊断分布显示两组之间在精神病理类型和程度方面存在显著差异。
A group of 207 subjects with severely schizophrenic mothers and a matched group of 104 subjects without known mental illness in the parents or grandparents have been followed since 1962 in a prospective study based on Mednick's learning theory of schizophrenia. The present paper describes an analysis of the clinical outcome based on a follow‐up examination in 1972–1974. The examination consisted of a 3 1/2‐hour clinical interview using three approaches (two with computer‐derived diagnoses and one traditional clinical interview). 173 high‐risk and 91 low‐risk subjects were fully clinically reassessed. At the time of the assessment they were between 18 and 30 years old. The diagnostic distribution showed marked differences between the two groups with regard to type and degree of psychopathology.