Use of Low‐Dose Technetium Tc 99m Sulfur Colloid to Locate Sentinel Lymph Nodes in Melanoma of the Head and Neck: Preliminary Study

Use of Low‐Dose Technetium Tc 99m Sulfur Colloid to Locate Sentinel Lymph Nodes in Melanoma of the Head and Neck: Preliminary Study
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使用低剂量锝 Tc 99m 硫胶体定位头颈部黑色素瘤的前哨淋巴结:初步研究

DOI:
10.1097/00005537-200108000-00010
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发表时间:
2001
期刊:
The Laryngoscope
影响因子:
--
通讯作者:
B. Rasgon
B. Rasgon
中科院分区:
--
文献类型:
--
作者:
B. Rasgon

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目标/假设 由于前哨淋巴结是最先引流原发癌症部位的淋巴结,因此前哨淋巴结 (SLN) 活检的结果可表明区域淋巴结的状态。术前淋巴闪烁显像和术中联合应用手持式伽玛探针和蓝色染料技术(即“联合技术”)以前被用来准确识别前哨淋巴结,主要是在四肢和躯干的黑色素瘤中,有时也用于解剖结构复杂的头部或颈部黑色素瘤。由于这种复杂性,头部或颈部黑色素瘤的治疗本身就存在问题:前哨淋巴结的定位可能很困难或不可能,因为原发癌症部位可能靠近或与淋巴结盆地重叠。本研究的目的是确定技术修改和其他考虑因素,使前哨淋巴结定位在发生在头部或颈部淋巴结盆附近或重叠的黑色素瘤的情况下可行。
Objectives/Hypothesis Because sentinel lymph nodes are the first lymph nodes that drain a primary cancer site, results of sentinel lymph node (SLN) biopsy indicate status of the regional lymph nodes. Preoperative lymphoscintigraphy and intraoperative combined application of the handheld gamma probe and blue‐dye technique (i.e., the “combined technique”) was used previously to accurately identify the SLN, mostly in melanoma of the extremities and trunk and, sometimes, in melanoma of the head or neck, which is anatomically complex. Because of this complexity, melanoma in the head or neck is inherently problematic to treat: Localization of the SLN can be difficult or impossible because the primary cancer site can be near or overlapping the nodal basin. The objective of the present study was to determine the technical modifications and other considerations that can make SLN localization feasible in cases of melanoma occurring near or overlapping the nodal basin in the head or neck.
DOI: 10.1001/archsurg.1992.01420040034005
发表时间: 1992-04
影响因子: --
作者:
D. Morton;Wenger Dr;J. Wong;J. Economou;L. Cagle;Storm Fk;L. Foshag;A. Cochran
通讯作者: D. Morton;Wenger Dr;J. Wong;J. Economou;L. Cagle;Storm Fk;L. Foshag;A. Cochran