Quinine-catalyzed enantioselective desymmetrization of meso-aziridines with benzenethiols
Quinine-catalyzed enantioselective desymmetrization of meso-aziridines with benzenethiols
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DOI：
10.1016/j.tetasy.2008.03.017
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发表时间：
2008-05-01
影响因子：
--
通讯作者：
Wu, Jie
中科院分区：
文献类型：
--
作者：
Wang, Zhiyong;Sun, Xiaoyu;Wu, Jie
已经开发出利用奎宁作为有机催化剂的内消旋氮丙啶与苯硫醇的开环。在 10 mol% 奎宁的 CHCl3 溶液存在下，反应顺利进行，以高产率和中等至良好的对映选择性生成 β-氨基硫化物。 (C) 2008 Elsevier Ltd. 保留所有权利。
Ring opening of meso-aziridines with benzenethiols utilizing quinine as an organocatalyst has been developed. The reaction proceeded smoothly in the presence of 10 mol % of quinine in CHCl3 to afford beta-amino sulfides in high yields and with moderate to good enantioselectivities. (C) 2008 Elsevier Ltd. All rights reserved.