High-dose-rate brachytherapy for patients with maxillary gingival carcinoma using a novel customized intraoral mold technique
High-dose-rate brachytherapy for patients with maxillary gingival carcinoma using a novel customized intraoral mold technique
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DOI：
10.1016/j.tripleo.2009.10.019
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发表时间：
2010-02-01
期刊：
影响因子：
--
通讯作者：
Honda, Eiichi
中科院分区：
文献类型：
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作者：
Kudoh, Takaharu;Ikushima, Hitoshi;Honda, Eiichi
Objective.本研究的目的是介绍一种新的定制口腔内模具治疗上颌牙龈癌（UGC）。采用该技术对2例UGC患者进行了挽救治疗。模具的设计是为了使肿瘤附近的正常软组织尽可能远离放射源，它被铅屏蔽。在开始高剂量率近距离放射治疗前，通过远程后装系统测量口腔内模具内外表面颊粘膜和舌的辐射剂量，并将其降低至近十分之一。随访期间，患者无复发，肿瘤周围正常软组织无严重不良反应。使用新型定制口腔内模具的高剂量率近距离放射治疗可能不仅是UGC的挽救治疗，而且是UGC的确定性治疗的治疗选择。(Oral外科口腔医学口腔病理学口腔放射学Endod 2010; 109：e102-e108）
Objective. The purpose of this study was to introduce a novel customized intraoral mold treatment for maxillary gingival carcinoma (UGC).Study design. Two patients with UGC were treated as salvage therapy using this technique. The mold was designed to keep normal soft tissues adjacent to the tumor away from the radioactive source as much as possible, and it was shielded by lead. The radiation dose on the buccal mucosa and tongue was measured at the inner and outer surfaces of the intraoral mold before starting high-dose-rate brachytherapy by the remote afterloading system, and was reduced to almost one tenth.Results. The patient had no recurrence and no severe adverse effects on the normal soft tissue adjacent to the tumor until the end of the follow-up period.Conclusion. High-dose-rate brachytherapy using the novel customized intraoral mold might be a treatment option of not only salvage therapy, but definitive therapy of UGC. (Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2010; 109: e102-e108)