Mechanisms of incisional pain.
Mechanisms of incisional pain.
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DOI：
10.1016/j.atc.2004.11.009
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发表时间：
2005-03-01
期刊：
影响因子：
--
通讯作者：
Pogatzki-Zahn, Esther M
中科院分区：
文献类型：
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作者：
Brennan, Timothy J;Zahn, Peter K;Pogatzki-Zahn, Esther M
术后切口疼痛是一种独特但常见的急性疼痛形式。由于有效的术后镇痛降低了手术后的发病率，因此继续寻求新的治疗方法。通过研究模型的发展和机制的研究，可以推进围手术期医学。本文综述了大鼠足底后爪术后疼痛模型的研究，并提出了切口引起感觉神经元兴奋性增强的机制。
Postoperative, incisional pain is a unique but common form of acute pain. Because effective postoperative analgesia reduces morbidity following surgery, new treatments continue to be sought. It is through the development of investigational models and studies of the mechanisms that perioperative medicine can be advanced. This article reviews studies on a rat plantar hindpaw model for postoperative pain and proposes mechanisms for enhanced excitability of sensory neurons caused by incisions.