Deep Eutectic Solvents as Active Pharmaceutical Ingredient Delivery Systems in the Treatment of Metabolic Related Diseases.
Deep Eutectic Solvents as Active Pharmaceutical Ingredient Delivery Systems in the Treatment of Metabolic Related Diseases.
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低共熔溶剂作为活性药物成分输送系统用于治疗代谢相关疾病
DOI：
10.3389/fphar.2021.794939
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发表时间：
2021
影响因子：
5.6
通讯作者：
Gao H
中科院分区：
文献类型：
--
作者：
Huang C;Chen X;Wei C;Wang H;Gao H
Metabolic related diseases such as cancer, diabetes mellitus and atherosclerosis are major challenges for human health and safety worldwide due to their associations with high morbidity and mortality. It is of great significance to develop the effective active pharmaceutical ingredient (API) delivery systems for treatment of metabolic diseases. With their unique merits like easy preparation, high adjustability, low toxicity, low cost, satisfactory stability and biodegradation, deep eutectic solvents (DESs) are unarguably green and sustainable API delivery systems that have been developed to improve drug solubility and treat metabolic related diseases including cancer, diabetes mellitus and atherosclerosis. Many reports about DESs as API delivery systems in the therapy of cancer, diabetes mellitus and atherosclerosis exist but no systematic overview of these results is available, which motivated the current work.
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影响因子：
5.8
作者：
Li, Zheng;Lee, Ping I.
通讯作者：
Lee, Ping I.
影响因子：
20.1
作者：
Kane AE;Sinclair DA
通讯作者：
Sinclair DA
DOI：
10.1016/j.ejpb.2017.02.003
发表时间：
2017-05-01
影响因子：
4.9
作者：
Duarte, Ana Rita C.;Ferreira, Ana Sofia D.;Paiva, Alexandre
通讯作者：
Paiva, Alexandre
影响因子：
5.4
作者：
Edupuganti, Om P.;Ovsepian, Saak V.;Dolly, J. Oliver
通讯作者：
Dolly, J. Oliver
影响因子：
3.8
作者：
KaplunFrischoff, Y;Touitou, E
通讯作者：
Touitou, E