Methodology for generating a 3D computerized breast phantom from empirical data
Methodology for generating a 3D computerized breast phantom from empirical data
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DOI：
10.1118/1.3140588
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发表时间：
2009-07-01
期刊：
影响因子：
3.8
通讯作者：
Dobbins, James T., III
中科院分区：
文献类型：
--
作者：
Li, Christina M.;Segars, W. Paul;Dobbins, James T., III
描述了基于经验数据创建柔性三维计算机生成乳房幻影的初始过程。对乳房专用计算机断层扫描数据进行处理，以抑制重建图像集中的噪声和散射伪影。开发了一种自动算法将乳房分类为其主要组成部分。从分割的数据中生成了一个使用细分曲面定义的初步幻像。为了展示假体的潜在应用，我们使用简单的压缩模型和直接在表面模型上的解析投影算法来获取假体的模拟乳房x线图像数据。利用压缩模体的多能锥束投影模型生成模拟图像。用于创建乳房幻影的方法产生的结果图像具有高水平的组织结构细节，并且看起来与实际的乳房x光检查相似。模拟幻影图像的分形维数测量值与真实人体受试者图像的测量值比较相似。一个真实的、几何定义的乳房假体可以准确地模拟成像数据，在乳房成像研究中有许多应用。
The initial process for creating a flexible three-dimensional computer-generated breast phantom based on empirical data is described. Dedicated breast computed-tomography data were processed to suppress noise and scatter artifacts in the reconstructed image set. An automated algorithm was developed to classify the breast into its primary components. A preliminary phantom defined using subdivision surfaces was generated from the segmented data. To demonstrate potential applications of the phantom, simulated mammographic image data were acquired of the phantom using a simplistic compression model and an analytic projection algorithm directly on the surface model. The simulated image was generated using a model for a polyenergetic cone-beam projection of the compressed phantom. The methods used to create the breast phantom generate resulting images that have a high level of tissue structure detail available and appear similar to actual mammograms. Fractal dimension measurements of simulated images of the phantom are comparatively similar to measurements from images of real human subjects. A realistic and geometrically defined breast phantom that can accurately simulate imaging data may have many applications in breast imaging research.