A QUANTITATIVE-ANALYSIS OF THE IPSILATERAL RETINOCOLLICULAR PROJECTION IN THE CAT - AN EM DEGENERATION AND EM AUTORADIOGRAPHIC STUDY
A QUANTITATIVE-ANALYSIS OF THE IPSILATERAL RETINOCOLLICULAR PROJECTION IN THE CAT - AN EM DEGENERATION AND EM AUTORADIOGRAPHIC STUDY
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DOI：
10.1002/cne.902060305
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发表时间：
1982-01-01
影响因子：
2.5
通讯作者：
BEHAN, M
中科院分区：
文献类型：
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作者：
BEHAN, M
应用电镜变性和电镜放射自显影技术，对猫同侧上级丘向双眼段的投射进行了定量研究。由于同侧终末呈斑片状分布，因此在丘的内外侧范围内采集连续样本。EM退变和EM放射自显影的结果基本一致。在双眼节段中，同侧投射分别占到上级丘的总视网膜输入的5.3%和5.6%。由于对侧投射在整个丘上延伸，但在尾侧区域最大，而同侧投射仅限于丘的中间1/3，因此同侧视网膜丘总投射小于早期估计值（5- 10%，Kanaseki和Sprague，“74），可能更接近1%，如Sterling基于EM变性研究所建议的。对侧浅灰质中每个轴突的终末数比同侧浅灰质中多得多。在对侧，SGS 1和SGS 2中退化的终末与SGS 3中退化的轴突的比率为3.1，而在同侧丘中，该数字为1.2。这可能反映了Y型和W型视网膜神经节细胞在丘的树枝状模式的差异。
The ipsilateral projection to the binocular segment of the superior colliculus in the cat was quantified by EM degeneration and EM autoradiography. Because of the patchy distribution of ipsilateral terminals, contiguous samples were taken across the mediolateral extent of the colliculus. The results from both EM degeneration and EM autoradiography are in substantial agreement. In the binocular segment, the ipsilateral projection represents 5.3% and 5.6%, respectively, of the total retinal input to the superior colliculus. As the contralateral projection extends over the whole colliculus but is greatest in the caudal region, while the ipsilateral projection is restricted to the middle 1/3 of the colliculus, it follows that the total ipsilateral retinocollicular projection is less than earlier estimates (5-10%, Kanaseki and Sprague, ''74) and probably closer to 1%, as suggested by Sterling on the basis of an EM degeneration study. There are many more terminals per axon in the contralateral than in the ipsilateral superficial gray. The ratio of degenerated terminals in SGS1 and SGS2 to degenerated axons in SGS3 is 3.1 contralaterally, while in the ipsilateral colliculus the figure is 1.2. This may reflect a difference in the arborization pattern of Y-type and W-type retinal ganglion cells in the colliculus.