Organoselenium Compounds in Biology and Medicine: Synthesis, Biological and Therapeutic Treatments
Organoselenium Compounds in Biology and Medicine: Synthesis, Biological and Therapeutic Treatments
复制标题
DOI：
10.1039/9781788011907
复制
发表时间：
2017
期刊：
影响因子：
--
通讯作者：
V. Jain;K. Priyadarsini
中科院分区：
文献类型：
--
作者：
V. Jain;K. Priyadarsini
有机硒在医学上显示出令人难以置信的前景，特别是癌症治疗。这本书讨论了有机硒化学和生物学在其治疗潜力的背景下，通过合成技术，生物活性和治疗应用的读者。分为三个部分，第一部分描述了生物活性硒化合物的合成进展，揭示了如何有机硒化合物的毒性，氧化还原特性和特异性可以进一步调整。第二部分解释了有机硒化合物和硒蛋白的生物物理学和生物化学。最后一节结束了几个章节致力于治疗和医药应用的有机硒化合物，包括辐射防护剂，抗癌剂和抗氧化剂的行为。随着来自全球领先专家的贡献，这本书涵盖了该领域的最新进展，是那些研究有机硒化合物的理想参考。
Organoselenium shows incredible promise in medicine, particularly cancer therapy. This book discusses organoselenium chemistry and biology in the context of its therapeutic potential, taking the reader through synthetic techniques, bioactivity and therapeutic applications. Divided into three sections, the first section describes synthetic advances in bioactive selenium compounds, revealing how organoselenium compound toxicity, redox properties and specificity can be further tuned. The second section explains the biophysics and biochemistry of organoselenium compounds, as well as selenoproteins. The final section closes with several chapters devoted to therapeutic and medicinal applications of organoselenium compounds, covering radioprotectors, anticancer agents and antioxidant behaviour. With contributions from leading global experts, this book covers recent advances in the field and is an ideal reference for those researching organoselenium compounds.