Relative fat mass (RFM) as a new estimator of whole-body fat percentage - A cross-sectional study in American adult individuals
Relative fat mass (RFM) as a new estimator of whole-body fat percentage - A cross-sectional study in American adult individuals
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DOI：
10.1038/s41598-018-29362-1
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发表时间：
2018-07-20
影响因子：
4.6
通讯作者：
Bergman, Richard N.
中科院分区：
文献类型：
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作者：
Woolcott, Orison O.;Bergman, Richard N.
高全身脂肪百分比与死亡率增加独立相关。我们的目的是确定一个简单的人体测量线性方程，它比身体质量指数（BMI）更准确地估计成年人的全身脂肪百分比。模型开发使用1999-2004年国家健康与营养调查（NHANES）数据（n = 12581），模型验证使用NHANES 2005-2006年数据（n = 3456）。从生成的365个人体测量指标中，最终选定的方程为：64 - （20 ×身高/腰围）+ （12 ×性别），称为相对脂肪质量（RFM）；性别=男性0，女性1。在验证数据集中，与BMI相比，RFM更好地预测了女性和男性的全身脂肪百分比，通过双能x射线吸收仪（DXA）测量。RFM显示出比BMI更好的准确性，并且在女性和男性中都有更少的假阴性体脂定义的肥胖病例。RFM减少了所有女性和所有男性的肥胖错误分类，总体而言，墨西哥裔美国人、欧洲裔美国人和非洲裔美国人的肥胖错误分类。在研究的人群中，建议的RFM比BMI更准确地估计了女性和男性的全身脂肪百分比，并改善了墨西哥、欧洲或非洲种族的美国成年人体内脂肪定义的肥胖错误分类。
High whole-body fat percentage is independently associated with increased mortality. We aimed to identify a simple anthropometric linear equation that is more accurate than the body mass index (BMI) to estimate whole-body fat percentage among adult individuals. National Health and Nutrition Examination Survey (NHANES) 1999-2004 data (n = 12,581) were used for model development and NHANES 2005-2006 data (n = 3,456) were used for model validation. From the 365 anthropometric indices generated, the final selected equation was as follows: 64 - (20 x height/waist circumference) + (12 x sex), named as the relative fat mass (RFM); sex= 0 for men and 1 for women. In the validation dataset, compared with BMI, RFM better predicted whole-body fat percentage, measured by dual energy X-ray absorptiometry (DXA), among women and men. RFM showed better accuracy than the BMI and had fewer false negative cases of body fat-defined obesity among women and men. RFM reduced total obesity misclassification among all women and all men and, overall, among Mexican-Americans, European-Americans and African-Americans. In the population studied, the suggested RFM was more accurate than BMI to estimate whole-body fat percentage among women and men and improved body fat-defined obesity misclassification among American adult individuals of Mexican, European or African ethnicity.