Application of a search algorithm using stochastic behaviors to autonomous control of a ventricular assist device

Application of a search algorithm using stochastic behaviors to autonomous control of a ventricular assist device
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使用随机行为的搜索算法在心室辅助装置自主控制中的应用

DOI:
10.1109/embc.2014.6943586
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发表时间:
2014
期刊:
conf proc ieee eng med biol soc.
影响因子:
--
通讯作者:
Tatsumi E
Tatsumi E
中科院分区:
--
文献类型:
--
作者:
Ohnuma K;Sumikura H;Homma A;Tsukiya T;Mizuno T;Takewa Y;Tatsumi E

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心室辅助装置 (VAD) 是一种将机械泵植入患者原生心脏附近以支持血流的装置。 Mechanical circulatory support using VADs has been an essential therapeutic tool for patients with severe heart failure waiting for a heart transplant in clinical site. Adaptive control of VADs that automatically adjust the pump output with changes in a patient state is one of the important approaches for enhanced therapeutic efficacy, prevention of complications and quality of life improvement. However adaptively controlling a VAD in the realistic situation would be difficult because it is necessary to model the whole including the VAD and the cardiovascular dynamics.为了解决这个问题,我们提出了一种利用随机行为的吸引子选择算法在 VAD 控制系统中的应用。 In this study, we sought to investigate whether this proposed method can be used to adaptively control of a VAD in the simple case of a continuous flow VAD.作为一个应用示例,流量控制算法是在随机搜索算法的基础上构建的。在模拟电路中检验了所构建的控制算法的有效性。 As a result, in response to a low-flow state with the different causes, the flow rate of the pump reached a target value with self adaptive behavior without designing the detailed control rule based on the experience or the model of the control target.
A ventricular assist device (VAD) is a device with mechanical pumps implanted adjacent to the patient's native heart to support the blood flow. Mechanical circulatory support using VADs has been an essential therapeutic tool for patients with severe heart failure waiting for a heart transplant in clinical site. Adaptive control of VADs that automatically adjust the pump output with changes in a patient state is one of the important approaches for enhanced therapeutic efficacy, prevention of complications and quality of life improvement. However adaptively controlling a VAD in the realistic situation would be difficult because it is necessary to model the whole including the VAD and the cardiovascular dynamics. To solve this problem, we propose an application of attractor selection algorithm using stochastic behavior to a VAD control system. In this study, we sought to investigate whether this proposed method can be used to adaptively control of a VAD in the simple case of a continuous flow VAD. The flow rate control algorithm was constructed on the basis of a stochastically searching algorithm as one example of application. The validity of the constructed control algorithm was examined in a mock circuit. As a result, in response to a low-flow state with the different causes, the flow rate of the pump reached a target value with self adaptive behavior without designing the detailed control rule based on the experience or the model of the control target.
基因网络对环境变化的自适应反应通过健身诱导的吸引子选择。
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