Short Report: Fatal Nosocomial Spread of Crimean-Congo Hemorrhagic Fever with Very Short Incubation Period
Short Report: Fatal Nosocomial Spread of Crimean-Congo Hemorrhagic Fever with Very Short Incubation Period
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DOI：
10.4269/ajtmh.2012.12-0337
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发表时间：
2013-03-01
影响因子：
3.3
通讯作者：
Mostafavi, Irandokht
中科院分区：
文献类型：
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作者：
Naderi, HamidReza;Sheybani, Fereshte;Mostafavi, Irandokht
克里米亚-刚果出血热是一种蜱传病毒性人畜共患病，具有人传人的潜力，病死率从 3% 到 50%。潜伏期取决于宿主、感染途径和病毒剂量。在此，我们报告了伊朗东北部马什哈德一家医院发生的疾病院内传播，其中一名继发病例的潜伏期非常短。该患者是一名医学生，入院期间与一名克里米亚-刚果出血热患者有过轻微接触。从接触到出现症状之间的时间间隔仅为20小时。不幸的是，他在暴露后 1 周内死亡。
Crimean-Congo hemorrhagic fever is a tick-borne viral zoonosis with the potential of human-to-human transmission with case fatality rates from 3% to 50%. The incubation period depends on host, route of infection, and viral dose. Herein, we report a nosocomial spread of the disease in a hospital at Mashhad, northeastern Iran, with a very short incubation period for one of the secondary cases. The patient was a medical student who had a negligible contact with a Crimean-Congo hemorrhagic fever patient during his admission to the hospital. The time interval between the contact and the onset of symptoms was merely 20 hours. Unfortunately, he died within 1 week of exposure.