Tooth loss after active periodontal therapy. 1: patient-related factors for risk, prognosis, and quality of outcome
Tooth loss after active periodontal therapy. 1: patient-related factors for risk, prognosis, and quality of outcome
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DOI：
10.1111/j.1600-051x.2007.01184.x
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发表时间：
2008-02-01
影响因子：
6.7
通讯作者：
Pretzl, Bernadette
中科院分区：
文献类型：
--
作者：
Eickholz, Peter;Kaltschmitt, Jens;Pretzl, Bernadette
目的：评估在开始抗感染治疗10年后(1)导致牙齿脱落和(2)影响治疗结果质量的患者相关因素。材料与方法：连续招募10年前由同一检查者进行牙周积极治疗的患者，直至重新检查100例患者。复查由另一名检查者进行，包括临床检查、白细胞介素-1 （IL-1）多态性检测、吸烟史、患者档案回顾（如支持牙周治疗的规律性：SPT）。统计分析采用泊松回归和logistic回归。结果：定期参加SPT的患者53例，女性59例，IL-1阳性38例。泊松回归发现，SPT期间的平均牙菌斑指数（p < 0.0001）、不规律参加SPT （p < 0.0001）、年龄（p < 0.0001）、初始诊断（p = 0.0005）、IL-1多态性（p = 0.0007）、吸烟（p = 0.0053）和性别（p = 0.0487）是导致牙齿脱落的重要因素。此外，SPT期间的平均斑块指数（p = 0.011）和不规则SPT （p = 0.002）与治疗开始后10年牙周状况恶化相关。结论：口腔卫生不良、SPT不规则、IL-1多态性、初诊、吸烟、年龄和性别是导致牙脱落的危险因素。
Objectives: Assessment of patient-related factors contributing (1) to tooth loss and (2) to the quality of treatment outcome 10 years after initiation of anti-infective therapy.Material and Methods: All patients who had received active periodontal treatment 10 years ago by the same examiner were recruited consecutively until a total of 100 patients were re-examined. Re-examination was performed by a second examiner and included clinical examination, test for interleukin-1 (IL-1) polymorphism, smoking history, review of patients' files (e.g. regularity of supportive periodontal therapy: SPT). Statistical analysis included Poisson and logistic regressions.Results: Fifty-three patients attended SPT regularly, 59 were females, 38 were IL-1 positive. Poisson regressions identified mean plaque index during SPT (p < 0.0001), irregular attendance of SPT (p < 0.0001), age (p < 0.0001), initial diagnosis (p = 0.0005), IL-1 polymorphism (p = 0.0007), smoking (p = 0.0053), and sex (p = 0.0487) as factors significantly contributing to tooth loss. Additionally, mean plaque index during SPT (p = 0.011) and irregular SPT (p = 0.002) were associated with a worse periodontal status 10 years after initiation of therapy.Conclusion: The following risk factors for tooth loss were identified: ineffective oral hygiene, irregular SPT, IL-1 polymorphism, initial diagnosis, smoking, age and sex.