Statistical methods for ranking differentially expressed genes.
Statistical methods for ranking differentially expressed genes.
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DOI:
10.1186/gb-2003-4-6-r41
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发表时间:
2003
期刊:
影响因子:
12.3
通讯作者:
Broberg P
中科院分区:
文献类型:
--
作者:
Broberg P
A method is outlined for finding an optimal test statistic with which to rank genes from microarray data with respect to differential expression. In the analysis of microarray data the identification of differential expression is paramount. Here I outline a method for finding an optimal test statistic with which to rank genes with respect to differential expression. Tests of the method show that it allows generation of top gene lists that give few false positives and few false negatives. Estimation of the false-negative as well as the false-positive rate lies at the heart of the method.
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DOI:
10.1073/pnas.011404098
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影响因子:
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通讯作者:
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