Tinnitus preceded depressive symptoms in community-dwelling older Japanese: A prospective cohort study
Tinnitus preceded depressive symptoms in community-dwelling older Japanese: A prospective cohort study
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DOI：
10.1016/j.ypmed.2013.01.016
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发表时间：
2013-05-01
影响因子：
5.1
通讯作者：
Takebayashi, Toru
中科院分区：
文献类型：
--
作者：
Michikawa, Takehiro;Nishiwaki, Yuji;Takebayashi, Toru
客观的。大多数关于耳鸣和抑郁之间关联的研究都是横断面的，因此很难就这种关联的方向性得出任何结论。本研究旨在澄清一般老年人群中耳鸣是否先于抑郁症状的发展。方法。日本群马县仓渊町的居民（男性239人，女性296人：65岁）在2005年至2006年期间接受了健康检查，其中没有抑郁症状。有关耳鸣的信息是。通过问卷调查获得。然后根据老年抑郁量表 15 项版本 (GDS15)，在 2007 年和 2008 年进行一次面对面的家访，对抑郁症状进行评估。结果。在男性中，有耳鸣的人 2.5 年抑郁症状的发生率 (GDS15 6) 高于没有耳鸣的人（20.5% vs. 9.5%）。在多重调整模型中，耳鸣与抑郁症状风险增加显着相关（相对风险 = 2.07；95% 置信区间 = 1.01-4.25）。在女性中，没有发现任何关联。结论。在本研究中，耳鸣与男性出现抑郁症状的风险独立相关，但与女性无关。我们认为初级保健提供者和公共卫生人员应该认识到耳鸣是抑郁症状的危险因素。 (C) 2013 Elsevier Inc. 保留所有权利。
Objective. Most studies of the association between tinnitus and depression have been cross-sectional, making it difficult to draw any conclusions about the directionality of the association. This study aimed to clarify whether tinnitus precedes the development of depressive symptoms in a general older population.Methods. Residents of Kurabuchi Town, Gunma Prefecture, Japan (239 men, 296 women: 65 years) without depressive symptoms were given health examinations in 2005-2006. Information on tinnitus was. obtained via a questionnaire. Depressive symptoms were then assessed in a face-to-face home visit interviews carried out once in 2007 and once in 2008 according to the Geriatric Depression Scale 15-item version (GDS15).Results. Among the men, the 2.5-year incidence of depressive symptoms (GDS15 6) was higher in those with tinnitus than in those without (20.5% vs. 9.5%). In the multi-adjusted model, tinnitus was significantly associated with an increased risk of depressive symptoms (relative risk = 2.07; 95% confidence interval = 1.01-4.25). Among the women, no associations were found.Conclusion. In the present study, tinnitus was independently associated with the risk of depressive symptoms developing in men, but not in women. We believe primary care providers and public health staff should recognize tinnitus as a risk factor for depressive symptoms. (C) 2013 Elsevier Inc. All rights reserved.