Dynamic contrast-enhanced magnetic resonance imaging: definitive imaging of placental function?
Dynamic contrast-enhanced magnetic resonance imaging: definitive imaging of placental function?
复制标题
DOI：
10.1016/j.siny.2010.09.001
复制
发表时间：
2011-02-01
影响因子：
3
通讯作者：
Salomon, L. J.
中科院分区：
文献类型：
--
作者：
Chalouhi, G. E.;Deloison, B.;Salomon, L. J.
胎盘在母亲和胎儿之间构成了一个复杂的循环界面，但母婴循环之间的关系仍然很难在体内进行研究。越来越多的证据表明，磁共振成像(MRI)在妊娠期是有用和安全的，MRI越来越多地用于胎儿和胎盘的解剖成像。磁共振功能成像现在是一种现代产科工具，有可能为人类胎盘的生理学提供新的见解。通过动脉自旋标记、扩散成像、使用回波平面成像测量T1和T2弛豫时间以及结合磁化转移和已有的体视学方法，研究了第一次MR造影剂的胎盘血流灌注。BOLD(血氧水平依赖)效应为胎盘的功能MRI评估提供了新的视角。(C)2010爱思唯尔有限公司。保留所有权利。
The placenta constitutes a complex circulatory interface between the mother and fetus, but the relationship between the maternal and fetal circulation is still very difficult to study in vivo. There is growing evidence that magnetic resonance imaging (MRI) is useful and safe during pregnancy, and MRI is increasingly used for fetal and placental anatomical imaging. MRI functional imaging is now a modern obstetric tool and has the potential to provide new insights into the physiology of the human placenta. Placental perfusion has been studied during the first pass of an MR contrast agent, by arterial spin labeling, diffusion imaging, T1 and T2 relaxation time measurement using echo-planar imaging, and by a combination of magnetization transfer with established stereological methods. The BOLD (blood oxygen level-dependent) effect offers new perspectives for functional MRI evaluation of the placenta. (C) 2010 Elsevier Ltd. All rights reserved.