Overview of OVATE FAMILY PROTEINS, A Novel Class of Plant-Specific Growth Regulators.
Overview of OVATE FAMILY PROTEINS, A Novel Class of Plant-Specific Growth Regulators.
复制标题
卵形家族蛋白概述，一类新型植物特异性生长调节剂
DOI：
10.3389/fpls.2016.00417
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发表时间：
2016
影响因子：
5.6
通讯作者：
Ellis B
中科院分区：
文献类型：
--
作者：
Wang S;Chang Y;Ellis B
OVATE家族蛋白（OFPs）是一类具有保守OVATE结构域的蛋白。OVATE蛋白首次在番茄中被鉴定为果实形状的关键调节因子。OFPs是植物特异性蛋白，广泛分布于植物界，包括苔藓和石松植物。对拟南芥原生质体中OFPs （AtOFPs）的转录活性分析表明，它们具有转录抑制因子的作用。来自拟南芥、水稻、番茄、辣椒和香蕉等不同植物物种的OFPs的功能表征表明，OFPs调控植物生长发育的多个方面，可能通过与KNOX和BELL类等不同类型的转录因子相互作用，或直接调控赤霉素20氧化酶（giberellin 20 oxidase, GA20ox）等靶基因的表达实现。在这里，我们研究了OVATE最初是如何被发现的，总结了OFPs在调节植物生长和发育中的作用的最新研究进展，并描述了这种调节的可能机制。最后，我们回顾了潜在的新的研究方向，以进一步阐明OFPs在植物中的功能生物学。
OVATE FAMILY PROTEINS (OFPs) are a class of proteins with a conserved OVATE domain. OVATE protein was first identified in tomato as a key regulator of fruit shape. OFPs are plant-specific proteins that are widely distributed in the plant kingdom including mosses and lycophytes. Transcriptional activity analysis of Arabidopsis OFPs (AtOFPs) in protoplasts suggests that they act as transcription repressors. Functional characterization of OFPs from different plant species including Arabidopsis, rice, tomato, pepper, and banana suggests that OFPs regulate multiple aspects of plant growth and development, which is likely achieved by interacting with different types of transcription factors including the KNOX and BELL classes, and/or directly regulating the expression of target genes such as Gibberellin 20 oxidase (GA20ox). Here, we examine how OVATE was originally identified, summarize recent progress in elucidation of the roles of OFPs in regulating plant growth and development, and describe possible mechanisms underpinning this regulation. Finally, we review potential new research directions that could shed additional light on the functional biology of OFPs in plants.