Association between the ratio of serum n-3 to n-6 polyunsaturated fatty acids and acute coronary syndrome in non-obese patients with coronary risk factor: a multicenter cross-sectional study
Association between the ratio of serum n-3 to n-6 polyunsaturated fatty acids and acute coronary syndrome in non-obese patients with coronary risk factor: a multicenter cross-sectional study
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DOI：
10.1186/s12872-020-01445-w
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发表时间：
2020-04-06
影响因子：
2.1
通讯作者：
Daida, Hiroyuki
中科院分区：
文献类型：
--
作者：
Nishizaki, Yuji;Shimada, Kazunori;Daida, Hiroyuki
背景研究表明，超重、肥胖或体重过轻是缺血性心血管疾病（CVD）的危险因素;然而，CVD也发生在理想体重指数（BMI）的受试者中。最近，n-3/n-6多不饱和脂肪酸（PUFA）的平衡作为心血管疾病的风险标志物受到了关注，但到目前为止，还没有研究调查BMI和n-3/n-6 PUFA平衡与心血管疾病风险之间的关系。
BackgroundPrevious studies have reported that being overweight, obese, or underweight is a risk factor for ischemic cardiovascular disease (CVD); however, CVD also occurs in subjects with ideal body mass index (BMI). Recently, the balance of n-3/n-6 polyunsaturated fatty acids (PUFAs) has received attention as a risk marker for CVD but, so far, no study has been conducted that investigates the association between BMI and the balance of n-3/n-6 PUFAs for CVD risk.MethodsWe evaluated the association between n-3/n-6 PUFA ratio and acute coronary syndrome (ACS) in three BMI-based groups (