Exhaled Carbon Monoxide Levels: As a Marker of Clinical Severity and Control of Asthma
Exhaled Carbon Monoxide Levels: As a Marker of Clinical Severity and Control of Asthma
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DOI：
10.1080/02770900802168687
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发表时间：
2008-01-01
影响因子：
1.9
通讯作者：
Kumar, Raj
中科院分区：
文献类型：
--
作者：
Grover, Ravneet Singh;Kumar, Raj
进行了一项研究，以评估呼出的一氧化碳（CO）水平在轻度和中度持续性支气管哮喘患者的管理中的作用。在吸入皮质类固醇治疗四周之前和之后进行肺量测定、呼出CO测量和症状评分。与对照组相比，轻度和中度持续性哮喘患者的呼出CO水平显着升高，但该水平与疾病严重程度无关。治疗四周后，两组呼出的CO水平均有所下降，但未发现统计学显著性下降。因此，临床上呼出气CO水平不是支气管哮喘的有用指标。
A study was conducted to evaluate the role of exhaled carbon monoxide (CO) levels in the management of patients with mild and moderate persistent bronchial asthma. Spirometry, exhaled CO measurements and symptom scoring was done before and after four weeks of treatment with inhaled corticosteroids. Exhaled CO levels were significantly elevated in patients of mild as well as moderate persistent asthma as compared to controls but the levels did not correlate with the disease severity. After four weeks of treatment, there was a decrease in exhaled CO levels in both the groups but the decrease was not found to be statistically significant. Therefore, clinically exhaled CO level is not a useful marker in bronchial asthma.