Dynamic Combinatorial Donor-Acceptor Catenanes in Water: Access to Unconventional and Unexpected Structures
Dynamic Combinatorial Donor-Acceptor Catenanes in Water: Access to Unconventional and Unexpected Structures
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DOI：
10.1021/jo101981p
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发表时间：
2011-03-04
影响因子：
3.6
通讯作者：
Sanders, Jeremy K. M.
中科院分区：
文献类型：
--
作者：
Au-Yeung, Ho Yu;Pantos, G. Dan;Sanders, Jeremy K. M.
在这里，我们描述了从动态组合文库(DCL)在水中组装新型给体-受体[2]链烷。这些新的链烷在至少一个互锁环中既含有给体组分，又含有受体组分，从而在其结构中具有不寻常和意外的it单元的DAAD或DADD堆积序列。通过以多种方式操纵DCL平衡，可以提高环戊二烯组装过程的效率：添加客体。改变构建块的化学计量比，或增加库浓度或溶剂的离子强度。研究发现，链环的形成及其组成取决于施主构造物的几何、尺寸和柔性方面的细微差异。
We describe here the assembly of new types of donor-acceptor [2]catenanes from dynamic combinatorial libraries (DCL) in water. These new catenanes contain both the donor and acceptor components in at least one of the interlocked rings, thereby possessing unusual and unexpected DAAD or DADD stacking sequences of the it units in their structures. The efficiency of the catenane assembly process can be enhanced by manipulating the DCL equilibrium in a variety of ways: adding a guest. changing the building block stoichiometries, or increasing the library concentration or the ionic strength of the solvent. The formation of catenanes and their constitutions are found to be dependent on subtle differences in the geometry, dimension, and flexibility of the donor building blocks.