Cardiovascular disease risk in young Indian women with polycystic ovary syndrome
Cardiovascular disease risk in young Indian women with polycystic ovary syndrome
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DOI：
10.3109/09513590.2013.831835
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发表时间：
2014-01-01
影响因子：
2
通讯作者：
Dabadghao, P.
中科院分区：
文献类型：
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作者：
Guleria, A. K.;Syal, S. K.;Dabadghao, P.
多囊卵巢综合征（PCOS）与心血管疾病（CVD）的重要危险因素相关，如胰岛素抵抗、高胰岛素血症、高血压和血脂异常。我们使用颈动脉内膜中层厚度（CIMT）和肱动脉血流介导的扩张（FMD）（亚临床动脉粥样硬化的标志物）研究了年轻PCOS女性（18-35岁）的CVD风险。50例PCOS患者（年龄：24.3+/-4岁;体重指数[BMI]：24.6 +/-14 kg/m2）与50例年龄和BMI匹配的健康对照组（年龄：24.6 +/-5岁; BMI：23.9 +/-4 kg/m2）进行比较。CIMT显著更高（0.55 +/- 0.09 mm vs 0.40 +/- 0.1 mm，p值
Polycystic ovary syndrome (PCOS) is associated with significant risk factors for cardiovascular disease (CVD) like insulin resistance, hyperinsulinism, hypertension and dyslipidemia. We studied CVD risk in young women (18-35 years age) with PCOS using carotid intima media thickness (CIMT) and brachial artery flow mediated dilation (FMD) which are markers of subclinical atherosclerosis. Fifty women with PCOS (age: 24.3+/-4 years; body mass index [BMI]: 24.6 +/- 1 4 kg/m(2)) were compared with 50 age and BMI matched healthy controls (age: 24.6 +/- 5 years; BMI: 23.9 +/- 4 kg/m(2)). CIMT was significantly higher (0.55 +/- 0.09 mm versus 0.40 +/- 0.1 mm, p value