Effects of video viewing smartphone application intervention involving positive word stimulation in people with subthreshold depression: A pilot randomized controlled trial
Effects of video viewing smartphone application intervention involving positive word stimulation in people with subthreshold depression: A pilot randomized controlled trial
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DOI：
10.1016/j.jad.2020.12.104
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发表时间：
2021-03-01
影响因子：
6.6
通讯作者：
Hirao, Kazuki
中科院分区：
文献类型：
--
作者：
Kageyama, Kaito;Kato, Yudai;Hirao, Kazuki
背景：智能手机应用程序（即，SPSRS）是为了帮助阈下抑郁症（StD）患者通过在视频中呈现积极的词语刺激来改善抑郁症状而开发的。然而，到目前为止，没有随机对照试验（RCT）进行调查SPSRS应用干预抑郁症状的人与性病。因此，进行了一项试点随机对照试验，以评估SPSRS应用干预对StD患者的初步疗效。（女性= 34.4%，平均年龄= 20.06，SD = 1.24）随机分配至SPSRS应用干预组，每天约10分钟，持续5周（实验组; n = 16）或不干预（等待列表对照组; n = 16）。主要结局是5周干预后流行病学研究中心抑郁量表（CES-D）评分较基线的变化。次要结果是干预5周后Kessler心理困扰筛查量表（K-6）评分和广泛性焦虑症7项量表（GAD-7）较基线的变化。实验组在CES-D、K-6和GAD-7评分方面表现出中等、小和小的改善（调整后的Hedge g =-0.64、-0.29和-0.40）。局限性：由于样本量小，观察到的效应必须被认为是初步的。结果表明，潜在的干预使用SPSRS应用程序，以减少抑郁症状的人与性病。未来的研究应该在一个全面的随机对照试验中重复这些发现。
Background: A smartphone application (i.e., SPSRS) was developed to help people with subthreshold depression (StD) improve depressive symptoms by presenting positive word stimuli in videos. However, to date, no randomized controlled trials (RCTs) were conducted to investigate SPSRS application interventions for depressive symptoms in people with StD. Therefore, a pilot RCT was conducted to assess the preliminary efficacy of the SPSRS application intervention for people with StD.Methods: In a pilot RCT, 32 participants (female = 34.4%, mean age = 20.06, SD = 1.24) with StD were randomized to SPSRS application intervention for approximately 10 min/a day for 5 weeks (experimental group; n = 16) or no intervention (wait list control group; n = 16). The primary outcome is the change from baseline in the Center for Epidemiologic Studies Depression Scale (CES-D) score after the 5-week intervention. The secondary outcomes are the change from baseline in the Kessler Screening Scale for Psychological Distress (K-6) score and the Generalized Anxiety Disorder 7-item scale (GAD-7) after the 5-week intervention.Results: No participants dropped out of the study. The experimental group displayed medium, small, and small improvements in CES-D, K-6, and GAD-7 scores (adjusted Hedge's g = -0.64, -0.29, and -0.40), respectively, compared with control.Limitations: The observed effects must be considered preliminary due to the small sample size.Conclusions: The results suggest the potential of intervention using the SPSRS application to reduce depressive symptoms in people with StD. Future studies should replicate these findings in a full-scale RCT.