Sonographic characterisation of radiation-induced carotid artery stenosis
Sonographic characterisation of radiation-induced carotid artery stenosis
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DOI：
10.1159/000047771
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发表时间：
2002-01-01
影响因子：
2.9
通讯作者：
Metreweli, C
中科院分区：
文献类型：
--
作者：
Lam, WWM;Liu, KH;Metreweli, C
背景和目的：目的：研究鼻咽癌（NPC）患者颈动脉放射性狭窄的分布、程度及超声特征，方法：对71例NPC患者颈动脉放射性狭窄的斑块分布、狭窄程度及最大狭窄时斑块的超声特征进行分析。结果：鼻咽癌患者颈动脉狭窄的发生率较高（77比50.7%），与对照组的142例患者的脑血管疾病或颈动脉bruit.Results的症状的超声结果进行了比较。颈总动脉最常受到辐射诱导狭窄的影响（93/142 vs.对照组37/284），而颈动脉球是对照组最常受影响的部位（56/284）。中重度狭窄的NPC患者明显更多（21/71 vs. 27/142）。对辐射诱导的斑块和动脉粥样硬化斑块的超声表现的分析显示，辐射后组的病变更弥漫。非钙化斑块和斑块内低回声灶也更频繁的post-radiation group.Conclusions：辐射引起的颈动脉狭窄是更广泛的分布，与更严重的管腔狭窄，并有不同的超声斑块特征相比，颈动脉狭窄无辐射暴露。版权所有（C）2002 S. Karger AG，巴塞尔。
Background and Purpose: To study the distribution, extent and sonographic characterisation of radiation-induced carotid artery stenosis in nasopharyngeal carcinoma (NPC) patients.Methods:The distribution of plaques, the extent of stenosis, and the sonographic characterisation of the plaque at maximum stenosis were recorded in 71 NPC patients. The results were compared with the ultrasound results of a control group of 142 patients presenting with symptoms of cerebrovascular disease or carotid bruit.Results: NPC patients had a higher incidence of carotid stenosis (77 vs. 50.7%). The common carotid arteries were most commonly affected by radiation-induced stenosis (93/142 vs. 37/284 in the control group), whereas the carotid bulb was the most commonly affected (56/284) site in the control group. Significantly more NPC patients had moderate-to-severe stenosis (21/71 vs. 27/142). Analysis of the sonographic appearance of radiation-induced and atherosclerotic plaques showed more diffuse involvement in the post-radiation group. Non-calcified plaques and intraplaque hypoechoic foci were also more frequent in the post-radiation group.Conclusions: Radiation-induced carotid stenosis is more diffuse in distribution, is associated with more severe luminal stenosis and has different sonographic plaque characterisation compared with carotid stenosis without radiation exposure. Copyright (C) 2002 S. Karger AG, Basel.