Uveitis in children:: Population-based study in Finland
Uveitis in children:: Population-based study in Finland
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DOI：
10.1034/j.1600-0420.2000.078001084.x
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发表时间：
2000-02-01
期刊：
影响因子：
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通讯作者：
Saari, KM
中科院分区：
文献类型：
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作者：
Päivönsalo-Hietanen, T;Tuominen, J;Saari, KM
目的：目的调查儿童不同类型葡萄膜炎的发病率和患病率，并与成人进行比较。在这项基于人群的回顾性研究中，收集了1980年至1980年间在图尔库大学医院眼科诊所就诊的图尔库大学医院区所有被诊断为葡萄膜炎的居民的医疗记录1982年和1988年进行了回顾。共有1122例葡萄膜炎被确定，55 16岁以下儿童占4.9%。儿童葡萄膜炎发病率为4.3/10万（95%置信区间[CI]，2.2至6.4），患病率为27.9（95% CI，17.1至38.6），与成人的患病率相比显著较低（发病率和患病率p=0.001）。绝大多数儿童（50例（90.9%））患有前葡萄膜炎（Au），Au的发病率和患病率显著低于成人（发病率和患病率p=0.001）。3名（5.5%）儿童患有后葡萄膜炎（PU），但与成人相比，儿童PU的发病率无显著差异，患病率仅略有显著差异（发病率p=0.33，患病率p=0.07）。仅1例（1.8%）出现中间型和1例全葡萄膜炎，无新发病例。儿童中最常见的诊断组是与幼年类风湿性关节炎、特发性急性前葡萄膜炎和特发性慢性前葡萄膜炎相关的Au。弓形体视网膜脉络膜炎在所有PU病例中均发现，发病率为0.3，患病率为1.1，与成人的发病率无显著差异（发病率p=1.0，患病率p = 0.48）。然而，与来自三级转诊中心的研究相反，在这项基于人群的研究中，儿童中不同形式的葡萄膜炎的分布似乎与成人中的分布相似。
Purpose: To investigate the incidence and prevalence rates of different types of uveitis in children, and to compare them with the rates in adults.Subjects and methods: For this population-based retrospective study the medical records of all residents of the district of Turku University Hospital with a diagnosis of uveitis seen at the Eye Clinic of Turku University Hospital during the years 1980-1982 and 1988 were reviewed.Results: A total of 1122 uveitis cases were identified, and 55 (4.9%) of them were children under 16 Sears, The incidence per 100 000 population per year for all uveitis cases in children was 4.3 (95% confidence interval [CI], 2.2 to 6.4), and the prevalence was 27.9 (95% CI, 17.1 to 38,6), which was significantly lower compared with the rates in adults (p=0.001 for incidence and prevalence). The vast majority of children, 50 (90.9%), had anterior uveitis (AU), and the incidence and prevalence rates of AU were significantly lower than in adults (p=0.001 for incidence and prevalence). Three (5.5%) children had posterior uveitis (PU), but there was no significant difference in the incidence and only marginally significant difference in the prevalence rate of PU in children compared with the rates in adults (p=0.33 for incidence, and p=0.07 for prevalence). Only one case (1.8%) was found with intermediate and one with panuveitis, but no new cases. The commonest diagnostic groups in children were AU associated with juvenile rheumatoid arthritis, idiopathic acute anterior uveitis, and idiopathic chronic anterior uveitis. Toxoplasmic retinochoroiditis was found in all of the PU cases with the incidence 0.3, and the prevalence 1.1, which did not differ significantly from the rates in adults (p=1.0 for incidence, and p 0.48 for prevalence).Conclusion: Uveitis is rarer in children than in adults. However, in contrast to studies from tertiary referral centers, the distribution of different forms of uveitis in children in this population-based study seems to resemble the distribution in adults.