Impact of new consent procedures on uptake of the schools-based human papillomavirus (HPV) vaccination programme.

Impact of new consent procedures on uptake of the schools-based human papillomavirus (HPV) vaccination programme.
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DOI:
10.1093/pubmed/fdaa164
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发表时间:
2022-03-07
期刊:
Journal of public health (Oxford, England)
影响因子:
--
通讯作者:
Audrey S
Audrey S
中科院分区:
其他
文献类型:
--
作者:
Fisher H;Hickman M;Ferrie J;Evans K;Bell M;Yates J;Roderick M;Reynolds R;MacLeod J;Audrey S

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2017-2018年期间,英格兰西南部两个地方当局在人乳头瘤病毒(HPV)疫苗接种计划年引入了启动新同意程序的地方政策变更。这项研究旨在评估对吸收和不平等的影响。检索了2015-2016年至2018-2019年方案年度的公开汇总和个人水平常规数据。进行统计分析,以显示:(一)与匹配的地方当局相比,地方当局在干预措施方面的变化;(二)总体上以及按地方当局、学校类型、种族和贫困程度分列的干预措施方面的变化。综合数据显示,在干预后阶段,地方当局一号的摄取率从76.3%增加到82.5%(风险差异:6.2%P = 0.17),差异效应差异为11.5%(P = 0.03)。没有证据表明地方当局2(P = 0.76)的差异中的差异效应。个体水平的数据显示,干预后总体摄入量增加(风险差异:+1.1%,P = 0.05),而在地方当局1上学的年轻女性(风险差异:2.3%,P < 0.01)。没有强有力的证据表明,按学校类别,种族群体和剥夺的变化被发现,实施新的同意程序可以改善和克服的趋势,减少匹配的地方当局之间的吸收。然而,没有证据表明减少不平等被发现。新的同意程序增加了在一个干预网站的摄取,并出现克服在匹配的网站摄取减少的趋势。在数据质量方面存在一些需要解决的问题。
Local policy change initiating new consent procedures was introduced during 2017–2018 for the human papillomavirus (HPV) vaccination programme year in two local authorities in the south–west of England. This study aims to assess impact on uptake and inequalities. Publicly available aggregate and individual-level routine data were retrieved for the programme years 2015–2016 to 2018–2019. Statistical analyses were undertaken to show: (i) change in uptake in intervention local authorities in comparison to matched local authorities and (ii) change in uptake overall, and by local authority, school type, ethnicity and deprivation. Aggregate data showed uptake in Local Authority One increased from 76.3% to 82.5% in the post-intervention period (risk difference: 6.2% P = 0.17), with a difference-in-differences effect of 11.5% (P = 0.03). There was no evidence for a difference-in-differences effect in Local Authority Two (P = 0.76). Individual-level data showed overall uptake increased post-intervention (risk difference: +1.1%, P = 0.05), and for young women attending school in Local Authority One (risk difference: 2.3%, P < 0.01). No strong evidence for change by school category, ethnic group and deprivation was found. Implementation of new consent procedures can improve and overcome trends for decreasing uptake among matched local authorities. However, no evidence for reduction in inequalities was found. The new consent procedures increased uptake in one of the intervention sites and appeared to overcome trends for decreasing uptake in matched sites. There are issues in relation to the quality of data which require addressing.
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发表时间: 2016-09
期刊: Journal of public health (Oxford, England)
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作者:
Batista Ferrer H;Trotter CL;Hickman M;Audrey S
通讯作者: Audrey S