DIRECTIONAL DIFFERENCES OF IMPULSE SPREAD IN TRABECULAR MUSCLE FROM MAMMALIAN HEART
DIRECTIONAL DIFFERENCES OF IMPULSE SPREAD IN TRABECULAR MUSCLE FROM MAMMALIAN HEART
复制标题
DOI：
10.1113/jphysiol.1976.sp011283
复制
发表时间：
1976-01-01
影响因子：
5.5
通讯作者：
CLERC, L
中科院分区：
文献类型：
--
作者：
CLERC, L
使用小牛心脏右心室的小梁束。将通过施加纵向电流测量的电性能与通过施加横向电流测量的电性能进行比较。以下数据是在经典电缆分析的基础上获得的：纵向与横向传导速度的比率为3.0，内部与外部纵向电阻的比率为3.6，内部与外部横向电阻的比率为12.6，细胞内横向电阻与细胞内纵向电阻之比为9.4，细胞外横向电阻与细胞外横向电阻之比为2.7。细胞纵向阻力传导速度的差异可以解释为细胞内和细胞外路径在2个方向上电流的电阻率差异的唯一理由，证实了理论预测。横向内阻的值可以根据三维网络中的频繁分支来解释。不需要另外假设电流流过平行光纤之间的横向低电阻路径。
Trabecular bundles from the right ventricle of calf hearts were used. Electrical properties measured by the application of longitudinal current were compared to those measured by the application of transverse current. The following data were obtained on the basis of classical cable analysis: a ratio of 3.0 for longitudinal to transverse conduction velocity, a ratio of 3.6 for intra- to extracellular longitudinal resistance, a ratio of 12.6 for intra- to extracellular transverse resistance, a ratio of 9.4 for intracellular transverse to intracellular longitudinal resistance and a ratio of 2.7 for the extracellular transverse to the extra-cellular longitudinal resistance. The disparity in conduction velocity could be explained on the sole grounds of differences in the resistivity of the intracellular and extra-cellular paths for current flow in the 2 directions, confirming theoritical predictions. The value of the transverse internal resistance can be accounted for on the ground of frequent branching in a 3-dimensional network. There is no need to make the additional assumption of current flow through lateral low resistance pathways between parallel fibers.