Physical impairment in patients with idiopathic inflammatory myopathies is associated with the American College of Rheumatology functional status measure
Physical impairment in patients with idiopathic inflammatory myopathies is associated with the American College of Rheumatology functional status measure
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DOI：
10.1007/s10067-014-2821-x
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发表时间：
2015-11-01
影响因子：
3.4
通讯作者：
Crofford, Leslie J.
中科院分区：
文献类型：
--
作者：
Hanaoka, Beatriz Y.;Cleary, Laura C.;Crofford, Leslie J.
本研究的目的是评估美国流变学学会功能状态（ACR-FS）图表摘要与患者报告的ACR-FS的预测价值，并将其与特发性炎性肌病（IIMs）患者的单机构队列中的肌肉功能指标相关联。通过回顾性病历审查获得了2006年至2012年期间在肯塔基州大学医学中心的流变学和神经病学诊所定期随访的102例IIM患者的人口统计学和临床数据。临床和功能状态评估，肌肉性能测试，身体成分的措施进行了一个子集的21名患者。ACR-FS通过图表提取和直接患者报告获得。采用斯皮尔曼相关性分析从图表提取与直接患者报告中得出的ACR-FS的关系，以及身体功能和身体成分测量与ACR-FS的关系。从图表提取得到的ACR-FS与从直接患者报告得到的ACR-FS显著相关（rho = 0.78，p < 0.001）。ACR-FS来自图表抽象也与患者报告的身体功能显著相关（rho =-0.71，p < 0.001）和体力活动（rho =-0.58，p < 0.05），手动肌肉测试（rho =-0.66，p < 0.01）和通过功能指数-2测试测量的骨骼肌耐力（肩屈曲rho =-0.62，p < 0.01;髋屈曲rho =-0.65，p < 0.0;脚跟抬起rho =-0.67，p < 0.01;和脚趾抬起rho =-0.68，p < 0.01）。ACR-FS是一种简单的残疾指标，可用于涉及IIM患者的图表抽象研究。我们已经证明，ACR-FS与力量和耐力的肌肉性能测试相关。
The goals of this study were to assess the predictive value of chart-abstracted American College of Rheumatology functional status (ACR-FS) with patient-reported ACR-FS and to relate it with measures of muscle function in a single-institution cohort of patients with idiopathic inflammatory myopathies (IIMs). Demographic and clinical data of 102 patients with IIMs regularly followed in the Rheumatology and Neurology Clinics at the University of Kentucky Medical Center between 2006 and 2012 were obtained through retrospective chart review. Clinical and functional status evaluation, muscle performance testing, and body composition measures were performed on a subset of 21 patients. ACR-FS was obtained by both chart abstraction and direct patient report. Spearman's correlations were used to examine the relationship of ACR-FS derived from chart abstraction with direct patient report, as well as the relationship of measures of physical function and body composition with ACR-FS. ACR-FS derived from chart abstraction was significantly correlated with ACR-FS derived from direct patient report (rho = 0.78, p < 0.001). ACR-FS derived from chart abstraction was also significantly correlated with patient-reported physical function (rho = -0.71, p < 0.001) and physical activity (rho = -0.58, p < 0.05), manual muscle testing (rho = -0.66, p < 0.01), and skeletal muscle endurance as measured by the functional index-2 test (shoulder flexion rho = -0.62, p < 0.01; hip flexion rho = -0.65, p < 0.0; heel lift rho = -0.67, p < 0.01; and toe lift rho = -0.68, p < 0.01). The ACR-FS is a simple measure of disability that can be used in chart abstraction studies involving IIM patients. We have demonstrated that ACR-FS correlates well with muscle performance tests of strength and endurance.