Visible-Light-Induced Photocatalytic Aerobic Oxidative C-sp3-H Functionalization of Glycine Derivatives: Synthesis of Substituted Quinolines
Visible-Light-Induced Photocatalytic Aerobic Oxidative C-sp3-H Functionalization of Glycine Derivatives: Synthesis of Substituted Quinolines
复制标题
可见光诱导光催化有氧氧化甘氨酸衍生物的 Csp3-H 功能化：取代喹啉的合成
DOI：
10.1021/acs.joc.6b02683
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发表时间：
2016
影响因子：
3.6
通讯作者：
Zhang Yuan
中科院分区：
文献类型：
--
作者：
Yang Xiaorong;Li Liqi;Li Ying;Zhang Yuan
实现了甘氨酸酯与未活化烯烃的可见光催化氧化脱氢偶联/芳构化串联反应。这种可见光驱动的方法已经成功地应用于甘氨酸酯和单烯烃的广泛应用，在温和的(空气气氛下室温下)和操作简单的反应条件下，产生了各种取代的喹啉衍生物，产率为18%-84%。
A visible-light induced photocatalytic aerobic oxidative dehydrogenative coupling/aromatization tandem reaction of glycine esters with unactivated alkenes has been accomplished. This visible light-driven protocol has been successfully applied to a broad scope of glycine esters and simple alkenes, giving rise to diverse substituted quinoline derivatives in 18–84% yield under mild (at room temperature under air atmosphere) and operationally simple reaction conditions.