Consolidation in human motor memory
Consolidation in human motor memory
复制标题
DOI：
10.1038/382252a0
复制
发表时间：
1996-07-18
期刊：
影响因子：
64.8
通讯作者：
Bizzi, E
中科院分区：
文献类型：
--
作者：
BrashersKrug, T;Shadmehr, R;Bizzi, E
在运动神经过程中学习运动技能，这些神经过程在练习结束后继续发展，这种现象被称为巩固（1-4）。在这里，我们提出了心理物理学的证据，并表明，巩固的运动技能被打断时，第二个运动任务后立即学习的第一个。如果在学习两种运动技能之间间隔4小时，则不会中断，在此期间会逐渐巩固。先前对人类和其他灵长类动物的研究发现，这种依赖于时间的巩固中断仅发生在外显记忆任务中（5-12），而外显记忆任务依赖于内侧颞叶的大脑结构（9，13，14）。我们的研究结果表明，不依赖于内侧颞叶（8，15）的运动记忆可以通过类似的巩固过程进行转化。通过将巩固现象扩展到运动记忆，我们的研究结果表明，不同的神经系统在编码和存储新信息时具有相似的特征。
LEARNING a motor skill sets in motion neural processes that continue to evolve after practice has ended, a phenomenon known as consolidation(1-4). Here we present psychophysical evidence for this, and show that consolidation of a motor skill was disrupted when a second motor task was learned immediately after the first. There was no disruption if four hours elapsed between learning the two motor skills, with consolidation occuring gradually over this period. Previous studies in humans and other primates have found this time-dependent disruption of consolidation only in explicit memory tasks(5-12), which rely on brain structures in the medial temporal lobe(9,13,14). Our results indicate that motor memories, which do not depend on the medial temporal lobe(8,15), can be transformed by a similar process of consolidation. By extending the phenomenon of consolidation to motor memory, our results indicate that distinct neural systems share similar characteristics when encoding and storing new information.