Voltage-gated ion channels in dendrites of hippocampal pyramidal neurons

Voltage-gated ion channels in dendrites of hippocampal pyramidal neurons
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DOI:
10.1007/s00424-006-0097-y
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发表时间:
2006-12-01
影响因子:
4.5
通讯作者:
Johnston, Daniel
Johnston, Daniel
中科院分区:
医学3区
文献类型:
--
作者:
Chen, Xixi;Johnston, Daniel

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电压门控离子通道的性质和分布有助于神经元树突中的电信号传递。海马CA1区锥体神经元的顶树突表达多种钠、钙、钾和其他电压门控通道。在这份报告中,我们提供了一些新的证据的作用,延迟整流钾通道在塑造树突状细胞动作电位在不同的膜电位。
The properties and distribution of voltage-gated ion channels contribute to electrical signaling in neuronal dendrites. The apical dendrites of CA1 pyramidal neurons in hippocampus express a wide variety of sodium, calcium, potassium, and other voltage-gated channels. In this report, we provide some new evidence for the role of the delayed-rectifier K+ channel in shaping the dendritic action potential at different membrane potentials.