Reducing the Risk of Contrast-Induced Nephropathy: A Perspective on the Controversies
Reducing the Risk of Contrast-Induced Nephropathy: A Perspective on the Controversies
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DOI：
10.2214/ajr.09.2368
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发表时间：
2009-06-01
影响因子：
5
通讯作者：
Cohan, Richard H.
中科院分区：
文献类型：
--
作者：
Ellis, James H.;Cohan, Richard H.
OBJECTIVE.造影剂肾病（CIN）尽管经过了数十年的研究，但仍知之甚少，诊断标准也各不相同。本文的目的是讨论目前关于造影剂肾病的争议，包括其预防。肾功能正常的患者发生CIN的风险极低。既存肾功能不全的患者似乎风险较高，其中一些患者可能需要采取预防措施;但是，如果有必要进行造影剂增强研究且没有其他选择，则不应停用碘化造影剂。
OBJECTIVE. Contrast-induced nephropathy (CIN) remains poorly understood despite decades of investigation, and the criteria for diagnosis are variable. The purpose of this article is to discuss current controversies in contrast-induced nephropathy including its prevention.CONCLUSION. Patients with normal renal function are at exceptionally low risk for CIN. Patients with preexisting renal insufficiency appear to be at higher risk and precautionary maneuvers may be warranted in some of these patients; however, iodinated contrast material should not be withheld if a contrast-enhanced study is necessary and there is no alternative.