Gastro-entero-pancreatic neuroendocrine neoplasia: The rules for non-operative management
Gastro-entero-pancreatic neuroendocrine neoplasia: The rules for non-operative management
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DOI：
10.1016/j.suronc.2020.08.015
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发表时间：
2020-12-01
影响因子：
2.3
通讯作者：
Falconi, Massimo
中科院分区：
文献类型：
--
作者：
Panzuto, Francesco;Massironi, Sara;Falconi, Massimo
胃肠胰腺神经内分泌肿瘤（GEP-NEN）具有良好的病理和临床特征，可被视为惰性病变，因此适合保守治疗。根据原发肿瘤的部位，不同的非侵略性的方法，内镜切除或简单的主动监测的基础上，可以建议选择符合特定标准的患者。肿瘤大小、Ki 67增殖指数和浸润深度是可用于识别这些受试者的标志物。I型胃NEN患者
Gastroenteropancreatic neuroendocrine neoplasms (GEP-NENs) with favorable pathological and clinical features may be considered as indolent lesions, and therefore be amenable to conservative management. According to the primary tumor site, different non-aggressive approaches, based on endoscopic resection or simple active surveillance, can be proposed to selected patients fulfilling specific criteria. Tumor size, Ki67 proliferative index and depth of invasion are markers that can be used in order to identify these subjects. Patients with type I gastric NENs