AN ENZYMATIC PATHWAY FROM L-XYLULOSE TO D-XYLULOSE1
AN ENZYMATIC PATHWAY FROM L-XYLULOSE TO D-XYLULOSE1
复制标题
从 L-木酮糖到 D-木酮糖的酶促途径1
DOI：
10.1021/ja01595a080
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发表时间：
1956
影响因子：
15
通讯作者：
O. Touster
中科院分区：
文献类型：
--
作者：
S. Hollmann;O. Touster
pentosuric” humans, 2· 3· 4 guinea pigs, 3 and rats, 4 together with the discovery of the presence, in guinea pig liver mitochondria, of a highly active enzymatic system for the reduction of L-xylulose to xylitol, 5 indicates that this ketopentose may be a normal metabolite. Recent work6· 7 has shown that D-xylulose-5-phosphate, rather than D-ribulose-5-phosphate, is the ketopentose substrate of transketolase (TK) in the 6-phosphogluconate pathway of carbohydrate metabolism. We wish to describe studies on new mitochondrial enzymes which link metabolically the enantiomorphic forms of xylulose. A stable, soluble enzyme preparation has been obtained by a butanol treatment of the insoluble portion of ruptured guinea pig liver mitochondria. It contains two enzymes which would makepossible
