Double identity for proteins of the Bcl-2 family
Double identity for proteins of the Bcl-2 family
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作者：
Reed, JC
BCL-2是一种致癌蛋白，通过抑制细胞程序性死亡发挥作用。这种蛋白和相关的抗凋亡蛋白用来保护细胞免受细胞毒刺激的机制现在正在形成，发现Bcl-2既可以作为离子通道，也可以作为适配器或对接蛋白。
Bcl-2 is an oncogenic protein that acts by inhibiting programmed cell death. The mechanisms used by this and related anti-apoptotic proteins to protect cells from cytotoxic stimuli are now emerging, with the discovery that Bcl-2 can function both as an ion channel and as an adaptor or docking protein.