Flow-cytometric analysis of mitochondria-associated fluorescence in young and old human fibroblasts.
Flow-cytometric analysis of mitochondria-associated fluorescence in young and old human fibroblasts.
复制标题
年轻和老年人类成纤维细胞线粒体相关荧光的流式细胞术分析。
DOI：
10.1016/0014-4827(86)90053-4
复制
发表时间：
1986
影响因子：
3.7
通讯作者：
Vila,JC
中科院分区：
文献类型：
--
作者：
Martinez,AO;Vigil,A;Vila,JC
用荧光激活细胞分类器(FACS)分析和定量罗丹明123在年轻和老年人成纤维细胞群体中的荧光。老年成纤维细胞表现出比年轻成纤维细胞更高的平均相对荧光。此外，在衰老细胞的荧光分布中有两个明显的亚群--但在年轻细胞中没有。
Rhodamine 123 fluorescence in populations of young and old human fibroblasts was analysed and quantified with a fluorescence-activated cell sorter (FACS). Old fibroblasts exhibited a higher mean relative fluorescence than young fibroblasts. Moreover, two distinct subpopulations were evident in the fluorescence distributions of old cells—but not in those of young cells.