Prevalence and determinants of isolated systolic hypertension among young adults: the 1999-2004 US National Health And Nutrition Examination Survey.
Prevalence and determinants of isolated systolic hypertension among young adults: the 1999-2004 US National Health And Nutrition Examination Survey.
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DOI：
10.1097/hjh.0b013e328331b7ff
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发表时间：
2010-01
影响因子：
4.9
通讯作者：
Pickering TG
中科院分区：
文献类型：
--
作者：
Grebla RC;Rodriguez CJ;Borrell LN;Pickering TG
年轻人的单纯收缩期高血压（ISH）知之甚少。我们使用1999-2004年国家健康和营养检查调查（NHANES）检查了该年龄组ISH的患病率和决定因素，并使用NHANES III（1988-1994）的数据进行了比较。分析了5，685名年龄在18-39岁且未服用抗高血压药物的成年人。ISH的患病率估计和潜在的危险因素估计的年龄和性别。为了将流行率估计值与已发表的NHANES III数据报告进行比较，还采用了按性别划分的年龄截止值（18-24岁、25-34岁和35-44岁）。多元Logistic回归模型测试ISH的独立决定因素。青年人ISH的患病率高于收缩期/舒张期高血压（1.57 ± 0.23% vs. 0.93 ± 0.18%）。在过去十年中，ISH患病率增加，尤其是每个年龄组的男性[男性（0.8% vs. 2.2%，1.3% vs. 2.4%，1.3% vs. 2.4%），女性（0.0% vs. 0.3%，0.1% vs. 0.7%，1.7% vs. 1.8%）]。在多变量分析中，肥胖（OR：2.68，95%CI：（1.06，6.77），男性（OR：2.19，95%CI：（1.10，4.37），文化程度高中以下（OR：2.98，95%CI：（1.10，8.06）和当前吸烟（OR：2.06，95%CI：（1.03，4.11））是与年轻成人ISH的高几率独立相关的特征。两次调查之间的患病率相对增加是由于目前吸烟（24.3%对51.5%）、肥胖（33.9%对42.7%）和教育水平低（18.4%对38.6%）。ISH在年轻人中的患病率正在增加，并且比收缩期/舒张期高血压更常见。肥胖、吸烟和低社会经济地位似乎是年轻人ISH的重要决定因素，并且在过去十年中都有所增加。
Little is known about isolated systolic hypertension (ISH) in younger adults. We examined the prevalence and determinants of ISH in this age group using the 1999-2004 National Health and Nutrition Examination Surveys (NHANES) and made comparisons using data from NHANES III (1988-1994). 5,685 adults aged 18-39 years and not on antihypertensive medications were analyzed. Prevalence estimates of ISH and potential risk factors were estimated by age and sex. For comparison of prevalence estimates with published reports of NHANES III data, age cutoffs (18-24, 25-34, and 35-44) by sex were also employed. A multivariate logistic regression model tested independent determinants of ISH. ISH in young adults had a higher prevalence than systolic/diastolic hypertension (1.57 ± 0.23% vs. 0.93 ± 0.18%). ISH prevalence increased within the last decade particularly for males for each respective age category [males (0.8% vs. 2.2%, 1.3% vs. 2.4%, 1.3% vs. 2.4%), females (0.0% vs. 0.3%, 0.1% vs. 0.7%, 1.7% vs. 1.8%)]. On multivariate analysis, obesity (OR: 2.68, 95% CI: (1.06, 6.77), male sex (OR: 2.19, 95% CI: (1.10, 4.37), education level less than high school (OR: 2.98, 95% CI: (1.10, 8.06), and current smoking (OR: 2.06, 95% CI: (1.03, 4.11) were characteristics independently associated with higher odds of ISH among young adults. Relative increases in prevalence between the surveys were noted for current smoking (24.3% vs. 51.5%), obesity (33.9% vs. 42.7%) and low educational level (18.4% vs. 38.6%). ISH among young adults is increasing in prevalence, and is more common than systolic/diastolic hypertension. Obesity, smoking, and low socioeconomic status appear to be important determinants of ISH among young adults and have all increased over the last decade.