FREQUENCY REPRESENTATION IN AUDITORY-CORTEX OF THE COMMON MARMOSET (CALLITHRIX-JACCHUS-JACCHUS)
FREQUENCY REPRESENTATION IN AUDITORY-CORTEX OF THE COMMON MARMOSET (CALLITHRIX-JACCHUS-JACCHUS)
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DOI：
10.1002/cne.902520204
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发表时间：
1986-10-08
影响因子：
2.5
通讯作者：
NELSON, JE
中科院分区：
文献类型：
--
作者：
AITKIN, LM;MERZENICH, MM;NELSON, JE
在5只麻醉的雄性成年动物上，通过绘制对侧耳纯音刺激时皮层单位和单位簇的反应图，确定了普通绒猴初级听觉皮层的位置和特征。初级听觉皮层大部分位于外侧沟的腹侧，外侧沟是这种大脑光滑的灵长类动物外侧皮层上唯一的主要裂缝，但在某些动物中，它可能会沿着这个沟的腹侧延伸。响应的分布使得低的最佳频率被发现rostroventrically而高的最佳频率发生在尾部。频带轮廓的分布是扇形的，低频倍频程的轮廓几乎平行于外侧沟，高频（> 8 kHz）轮廓垂直于该沟。最好的频率范围从0.6到30 kHz的主要领域，但有一个不成比例的代表性的三个倍频程之间的2和16 kHz。最敏感的阈值（低至-2 dB SPL）在7和9 kHz之间。初级听觉皮层的细胞结构与猫的相似，显示中间层（II-IV）的分层模糊，合并层中的小细胞占优势，呈现高度颗粒状的外观。在脑回表面上的耳蜗代表的可及性使得绒猴成为灵长类听觉皮层研究的有吸引力的动物。
The location and characteristics of the primary auditory cortex of the common marmoset, Callithrix jacchus jacchus, were determined in five anesthetized male adult animals by mapping the response of cortical units and unit clusters to pure tone stimuli presented to the contralateral ear. The primary auditory cortex lies largely ventral to the lateral sulcus, the only major fissure on the lateral cortex of this smooth-brained primate, but in some animals it may extend significantly down the ventral bank of this sulcus. Responses are distributed such that low best frequencies are found rostroventrically whereas high best frequencies occur caudally. The disposition of frequency-band contours is fan-shaped, with contours separating low-frequency octaves nearly parallel to the lateral sulcus and high-frequency (> 8 kHz) contours perpendicular to that sulcus. Best frequencies range from 0.6 to 30 kHz across the primary field, but there is a disproportionate representation of the three octaves between 2 and 16 kHz. The most sensitive threshold (as low as -2 dB SPL) are found between 7 and 9 kHz. The primary auditory cortex is similar in cytoarchitecture to that reported for the cat, showing a blurring of lamination in the middle layers (II-IV) and a preponderance of small cells in these merged layers, giving a highly granular appearance. The accessibility of the cochlear representation on the gyral surface makes the marmoset an attractive animal for studies of primate auditory cortex.