Adaptive evolution of multicolored fluorescent proteins in reef-building corals
Adaptive evolution of multicolored fluorescent proteins in reef-building corals
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DOI：
10.1007/s00239-005-0129-9
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发表时间：
2006-03-01
影响因子：
3.9
通讯作者：
Matz, MV
中科院分区：
文献类型：
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作者：
Field, SF;Bulina, MY;Matz, MV
在这里，我们研究了导致造礁珊瑚出现荧光颜色多样性的进化情景。我们发现，在积极的自然选择的帮助下，导致从祖先的绿色产生新的青色和红色表型的突变得到了修复。这一事实强烈表明颜色多样性是适应性进化的产物。一个意想不到的发现是一组排列为分子间结合界面的残基，这也被确定为正选择的目标，但与颜色多样化无关。我们假设，彩色荧光蛋白的进化是调节珊瑚与其藻类内共生体（虫黄藻）之间关系的机制的一部分。我们设想蛋白质荧光对藻类生理学的影响不仅可以通过光合作用调节来实现，还可以通过类似于高等植物的光敏色素和隐花色素的调节光传感器来实现。这样的监管需要相对微妙但精确的莫迪。光场的阳离子。这种机制的进化可以解释颜色的适应性多样化和珊瑚荧光蛋白中假定的藻类-蛋白质结合界面的共同进化追逐。
Here we investigate the evolutionary scenarios that led to the appearance of fluorescent color diversity in reef-building corals. We show that the mutations that have been responsible for the generation of new cyan and red phenotypes from the ancestral green were fixed with the help of positive natural selection. This fact strongly suggests that the color diversity is a product of adaptive evolution. An unexpected finding was a set of residues arranged as an intermolecular binding interface, which was also identified as a target of positive selection but is nevertheless not related to color diversification. We hypothesize that multicolored fluorescent proteins evolved as part of a mechanism regulating the relationships between the coral and its algal endosymbionts ( zooxanthellae). We envision that the effect of the proteins' fluorescence on algal physiology may be achieved not only through photosynthesis modulation, but also through regulatory photosensors analogous to phytochromes and cryptochromes of higher plants. Such a regulation would require relatively subtle, but spectrally precise, modi. cations of the light field. Evolution of such a mechanism would explain both the adaptive diversification of colors and the coevolutionary chase at the putative algae-protein binding interface in coral fluorescent proteins.